Details About Generic Salt ::  Quazepam

Main Medicine Class:: Sedative and hypnotic,benzodiazepine   

Class: Sedative and hypnotic/benzodiazepine


Drugs Class ::

 Action Potentiates action of GABA, an inhibitory neurotransmitter, resulting in increased neuronal inhibition and CNS depression, especially in limbic system and reticular formation.

Indications for Drugs ::

 Indications Short-term management of insomnia.

Drug Dose ::


ADULTS: PO 15 mg at bedtime initially; may reduce to 7.5 mg once individual response is determined. ELDERLY OR DEBILITATED PATIENT: Attempt dosage reduction after 1 to 2 nights.

Contraindication ::

 Contraindications Hypersensitivity to benzodiazepines; pregnancy; sleep apnea.

Drug Precautions ::


Pregnancy: Category X. Lactation: Excreted in breast milk. Children: Contraindicated in children < 18 yr. Special risk patients: Use drug with caution in patients with renal or hepatic impairment, depression or suicidal tendencies, drug abuse and dependence, chronic pulmonary insufficiency, seizure disorders. Dependence/Withdrawal: Prolonged use can lead to psychologic or physical dependence. Withdrawal syndrome may occur; dose must be tapered gradually.


Drug Side Effects ::

 Adverse Reactions

CV:Palpitations, tachycardia. CNS: Daytime drowsiness; dizziness; lethargy; confusion; memory impairment; euphoria; relaxed feeling; falling; ataxia; hallucinations; paradoxical reactions (eg, anger, hostility, mania); headache. DERM: Rash. EENT: Blurred vision; difficulty focusing. GI: Anorexia; diarrhea; abdominal cramping; constipation; nausea and vomiting. HEPA: Hepatic dysfunction. HEMA: Leukopenia; agranulocytopenia. OTHER: Tolerance; physical and psychological dependence; weakness; slurred speech.

Drug Mode of Action ::  

 Action Potentiates action of GABA, an inhibitory neurotransmitter, resulting in increased neuronal inhibition and CNS depression, especially in limbic system and reticular formation.

Drug Interactions ::


Alcohol, CNS depressants: May cause additive CNS depressant effects. Cimetidine, disulfiram, omeprazole: May increase quazepam effects. Digoxin: May increase serum digoxin concentrations. Theophylline: May antagonize sedative effects.

Drug Assesment ::


  • Obtain patient history, including drug history and any known allergies. Note potential for suicide or drug dependence.
  • Assess type of sleep difficulty: Falling asleep, remaining asleep.
  • Assess sleep pattern prior to and during therapy.
  • Assess mental status: Sensorium, affect, mood, and long-term and short-term memory.
  • Provide safety measures (removal of cigarettes, side rails up, night light, easily accessible call bell) and assistance with ambulation.

  Somnolence, confusion with reduced or absent reflexes, respiratory depression, apnea, hypotension, impaired coordination, slurred speech, seizures, coma

Drug Storage/Management ::


  • Administer ½ to 1 hr before bedtime with full glass of water. If GI upset occurs, administer with snack.
  • Check to see that medication is swallowed.
  • After long-term use, drug must be discontinued gradually. When drug is discontinued, expect nighttime sleep to be disturbed briefly (a few days).
  • Store in tight container in cool area.

Drug Notes ::

 Patient/Family Education

  • Caution patient that this medication must not be taken during pregnancy or when pregnancy is possible. Advise patient to use reliable form of birth control while taking this drug.
  • Discuss with patient ways to facilitate sleep (quiet, darkened room; avoidance of caffeine and nicotine; warm bath; warm milk; deep breathing; relaxation, self-hypnosis).
  • Instruct patient not to increase dose.
  • Emphasize importance of follow-up evaluation with health care provider to monitor progress of therapy. Instruct patient to inform health care provider if drug does not seem to be working.
  • Instruct patient not to discontinue medication abruptly after prolonged therapy (eg, > 2 wk).
  • Advise patient that disturbed nocturnal sleep may be experienced for 1 to 2 nights after discontinuing drug.
  • Instruct patient to report these symptoms to health care provider: Sudden onset of vision changes, irregular heart beat, fever, sore throat, bruising, rash, jaundice, unusual bleeding (eg, epistaxis), or if pregnancy is detected.
  • Advise patient to avoid intake of alcoholic beverages or other CNS depressants.
  • Advise patient that drug may cause drowsiness and to use caution while driving or performing other tasks requiring mental alertness.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.


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