Details About Generic Salt ::  Senna

Main Medicine Class:: Laxative   

(SEN-ah)
Agoral, Black-Draught, ex•lax, ex•lax chocolated, Fletcher Castoria, Senexon, Senna-Gen, Senokot, SenokotXTRA,  Glysennid, Mucinum Herbal
Class: Laxative

 

Drugs Class ::

 Action Directly acts on intestinal mucosa by altering water and electrolyte secretion, inducing peristalsis and defecation.

Indications for Drugs ::

 Indications Short-term treatment of constipation; preoperative and preradiographic bowel evacuation for procedures involving GI tract.

Drug Dose ::

 Route/Dosage

ADULTS: PO 2 tablets, 1 tsp of granules or 10 to 15 ml of syrup, usually at bedtime. PR 1 suppository at bedtime; may repeat in 2 hr. CHILDREN: Generally, for children 6 to 12 yr or > 60 lb, give (at bedtime) 1 tablet or ½ tsp granules PO or ½ suppository PR. Liquid dose ranges from 1.25 to 15 ml depending on age and product formulation.

Contraindication ::

 Contraindications Nausea, vomiting or other symptoms of appendicitis; acute surgical abdomen; fecal impaction; intestinal obstruction; undiagnosed abdominal pain.

Drug Precautions ::

 Precautions

Pregnancy: Category C. Lactation: Undetermined. Abuse/dependency: Long-term use may lead to laxative dependency, which may result in fluid and electrolyte imbalances, steatorrhea, osteomalacia and vitamin and mineral deficiencies. Cathartic colon, a poorly functioning colon, results from long-term abuse. Pathologic presentation may resemble ulcerative colitis. Discoloration of acidic urine: May result in yellow-brown urine. Discoloration of alkaline urine: May result in pink to red urine. Fluid and electrolyte imbalance: Excessive laxative use may lead to significant fluid and electrolyte imbalance. Melanosis Coli: Darkened pigmentation of colonic mucosa may occur after long-term use, usually resolving within 5 to 11 months of discontinuation. Rectal bleeding or failure to respond: May indicate serious condition requiring further attention.

PATIENT CARE CONSIDERATIONS


Drug Side Effects ::

 Adverse Reactions

CV: Palpitations. CNS: Dizziness; fainting. GI: Excessive bowel activity (eg, griping, diarrhea, nausea, vomiting); perianal irritation; bloating; flatulence; abdominal cramping. OTHER: Sweating; weakness.

Drug Mode of Action ::  

 Action Directly acts on intestinal mucosa by altering water and electrolyte secretion, inducing peristalsis and defecation.

Drug Interactions ::

 Interactions None well documented.

Drug Assesment ::

 Assessment/Interventions

  • Obtain patient history, including drug history and any known allergies.
  • Assess bowel function, including normal frequency, type, last bowel movement, bowel sounds, abdominal distention.
  • Assess for presence of abdominal pain, nausea, vomiting.
  • Assess for fluid and electrolyte imbalance associated with long-term laxative use.
  • Identify factors potentially contributing to constipation (ie, opioid analgesics), inactivity.
  • Monitor effectiveness of therapy.
  • Implement measures to prevent constipation, ie, fluids, activity, dietary bulk.
OVERDOSAGE: SIGNS & SYMPTOMS
  Gripping pain, diarrhea

Drug Storage/Management ::

 Administration/Storage

  • Administer at bedtime on empty stomach.
  • Shake liquid solution before administering.
  • Dissolve granules before administering.
  • For preoperative or prediagnostic bowel preparation, give between 2 to 4 PM on day before procedure.
  • Limit patient’s diet to clear liquids until after procedure.
  • Give oral dosages with full glass of water or juice.
  • Administer suppository with patient lying on left side.

Drug Notes ::

 Patient/Family Education

  • Explain potential hazards (eg, dependence) associated with long-term laxative use.
  • Advise that senna may result in discolored yellow-brown or reddish urine.
  • Explain that bowel patterns are very individual.
  • Identify measures to improve bowel function, ie, fluids, activity, dietary bulk.
  • Caution against taking laxatives in presence of acute abdominal pain or in presence of nausea or vomiting.

Disclaimer ::

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