The Brand Name CARNOSINE Has Generic Salt :: Adenosine 

CARNOSINE  Is From Company Samarth Priced :: Rs. 200

CARNOSINE have Adenosine is comes under Sub class Anti Arrhythmics of  Main Class Cardiovascular System

Main Medicine Class:: Cardiovascular System  Sub Medicine Class :: Anti Arrhythmics 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Adenosine  INJ  Rs. 200  2ML
Brand Name Company / Manufacturers Strength Unit Price / 2ML
 CARNOSINE  Samarth  6MG/2ML  2ML Rs. 200

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Samarth :: CARNOSINE  Adenosine  Cardiovascular System Anti Arrhythmics

Indications for Drugs ::

Paroxysmal supraventricular tachycardia,Supraventricular tachycardia

Drug Dose ::

Intravenous Differential diagnosis of supraventricular tachycardias Adult: Initially, 3 mg by rapid IV inj into a central or large peripheral vein over 2 sec with cardiac monitoring; 6 mg may be given after 1-2 minutes if necessary, then 12 mg after a further 1-2 minutes. Avoid increments if high level AV block occurs at any particular dose. Child: Initially, 50-100 mcg/kg; if necessary, may increase dose by 50-100 mcg/kg increments at 1-2 minute intervals or until arrhythmia is controlled. Max dose: 300 mcg/kg. Paroxysmal supraventricular tachycardia Adult: Initially, 3 mg by rapid IV inj into a central or large peripheral vein over 2 sec with cardiac monitoring; 6 mg may be given after 1-2 minutes if necessary, then 12 mg after a further 1-2 minutes. Avoid increments if high level AV block occurs at any particular dose. Child: Initially, 50-100 mcg/kg; if necessary, may increase dose by 50-100 mcg/kg increments at 1-2 minute intervals or until arrhythmia is controlled. Max dose: 300 mcg/kg. Myocardial imaging Adult: 140 mcg/kg/minute by infusion for 6 minutes. Inject radionuclide 3 minute after infusion.

Contraindication ::

2nd or 3rd degree AV block and sick sinus syndrome (unless pacemaker fitted), asthma, hypersensitivity.

Drug Precautions ::

Pregnancy; heart transplant patients; patients on dipyridamole (lower initial dose of adenosine 0.5-1 mg); atrial fibrillation or flutter with accessory pathway (conduction along anomalous pathway may increase).

Drug Side Effects ::

Facial flushing, palpitations, chest pain, bradycardia, sweating, hypotension, dyspnoea, choking sensation, headache, lightheadedness, tingling, numbness, neck and back pain, nausea, metallic taste. ECG changes suggestive of rhythm disturbances.

Pregnancy category ::
Pregnancy category

3

Drug Mode of Action ::  

Adenosine acts rapidly to slow down conduction through the AV node via the A1 receptors. It also mediates peripheral and coronary vasodilatation by stimulating the A2 receptors. Extremely short plasma half-life (<10 sec) permits dosage titration during IV use every 1-2 min and causes no concern of cumulative effect through repeated dosing. Drug Interactions ::

Adenosine effects antagonised by methylxanthines like caffeine, theophylline, etc. Concomitant carbamazepine may increase the risk of heart block. Potentially Fatal: Adenosine effects are potentiated by dipyridamole.

 

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