The Brand Name DITRATE Has Generic Salt :: Isosorbide 

DITRATE  Is From Company Panacea Priced :: Rs. 4.91

DITRATE have Isosorbide is comes under Sub class Anti Anginals of  Main Class Cardiovascular System

Main Medicine Class:: Cardiovascular System  Sub Medicine Class :: Anti Anginals 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Isosorbide  TAB  Rs. 4.91  100
Brand Name Company / Manufacturers Strength Unit Price / 100
 DITRATE  Panacea  5MG  100 Rs. 4.91

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Panacea :: DITRATE  Isosorbide  Cardiovascular System Anti Anginals

Indications for Drugs ::

Heart failure, Angina, Percutaneous transluminal coronary angioplasty

Drug Dose ::

Adult: PO Long term management of angina 20-120 mg/day in divided doses. Max: 240 mg/day. Heart failure 30-160 mg/day in divided doses. Max: 240 mg/day. Sublingual Heart failure 5-15 mg 2-3 hrly. Acute angina As tab: 2.5-10 mg. As spray: 1-3 sprays (1.25 mg/spray).

Contraindication ::

Severe hypotension or anaemia, hypovolaemia, heart failure due to obstruction, or raised intracranial pressure due to head trauma or cerebral haemorrhage.

Drug Precautions ::

Raised intracranial pressure, hypotension, hypovolaemia. Mitral valve prolapse, arterial hypoxaemia, glaucoma, elderly, hypothyroidism, malnutrition, pregnancy, lactation

Drug Side Effects ::

Hypotension, tachycardia, flushing, headache, dizziness, palpitation, syncope, confusion. Nausea, vomiting, abdominal pain. Apprehension, restlessness, weakness and vertigo. Potentially Fatal: Severe hypotension, circulatory collapse.

Pregnancy category ::
Pregnancy category

3

Drug Mode of Action ::  

Isosorbide dinitrate relaxes vascular smooth muscles by stimulating cyclic-GMP. It decreases left ventricular pressure (preload) and arterial resistance (afterload).

Drug Interactions ::

Increased hypotensive effects with alcohol or vasodilators. Marked orthostatic hypotension may occur when used with calcium channel blockers. Vasodilatory effect may be reduced with dihydroergotamine. Ergotamine effects may be enhanced. Reduced effectiveness of sublingual form with disopyramide. Potentially Fatal: Significant hypotension may occur with phosphodiesterase-5 inhibitors.

 

Disclaimer ::

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