Article Contents ::
Details About Generic Salt :: Fosinopril
Main Medicine Class:: Cardiovascular System Sub Medicine Class :: Anti Hypertensives
| 4D. ANTI-HYPERTENSIVES in 4. CARDIOVASCULAR SYSTEM |
| FOSINOPRIL |
| ACEI | ANTI-HYPERTENSIVE |
| also comes under 4A. Drugs for Cardiac Failure & Shock in 4. Cardiovascular System |
| PK: A: Well absorbed M: hepatic, intestine E: Urine, feces |
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Indications & Dose: HEART FAILURE PO Adult Initially 10mg/day & increase as needed, max 40mg OD over several wk usual dose 20-40mg/day | HYPERTENSION PO Adult Initially 10mg/day MD 20-40mg/day max 80mg/day Child >6 yr (>50kg): Initially 5-10mg/day max 40mg/day |
| Contra: Hypersensitivity, angioedema related to previous treatment with an ACE inhibitor
Precautions: Aortic stenosis, collagen vascular disease, CVD, hypertrophic cardiomyopathy, renal artery stenosis, renal impairment, before, during/immediately after major surgery ADR: Serious: Orthostatic hypotension, palpitation, Others: musculoskeletal pain, dizziness, diarrhea, nausea, vomiting, transaminases increased, weakness, cough, URTI DDI: Serious Antacids reduce drug bioavailability Diet: Monitor: BP, Se Cr & K, CBC |
