The Brand Name LOCK-2 Has Generic Salt :: Cimetidine 

LOCK-2  Is From Company Zydus Cadila Priced :: Rs. N.I.

LOCK-2 have Cimetidine is comes under Sub class GERD, of  Main Class Gastrointestinal System

Main Medicine Class:: Gastrointestinal System  Sub Medicine Class :: GERD, 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Cimetidine  TAB  Rs. N.I.  10
Brand Name Company / Manufacturers Strength Unit Price / 10
 LOCK-2  Zydus Cadila  200MG  10 Rs. N.I.

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Zydus Cadila :: LOCK-2  Cimetidine  Gastrointestinal System GERD,

Indications for Drugs ::

Heartburn, Dyspepsia, Peptic ulcers, Benign gastric and duodenal ulceration, Gastro-oesophageal reflux disease, Zollinger-Ellison syndrome, Pancreatic insufficiency

Drug Dose ::

Intravenous Benign gastric and duodenal ulceration Adult: Intermittent infusion: 300 mg 6-8 hrly infused over 15-20 min. Max: 2400 mg/day. Continuous infusion: 37.5 mg/hr (900 mg/day). A 150 mg IV loading dose may be given in patients requiring rapid elevation of gastric pH. Zollinger-Ellison syndrome Adult: Intermittent infusion: 300 mg 6-8 hrly infused over 15-20 min. Max: 2400 mg/day. Continuous infusion: 37.5 mg/hr (900 mg/day). A 150 mg IV loading dose may be given in patients requiring rapid elevation of gastric pH.

Contraindication ::

Hypersensitivity, lactation.

Drug Precautions ::

Impaired renal and hepatic function. Age >50 yr; CV impairment. Pregnancy.

Drug Side Effects ::

Diarrhoea, dizziness, tiredness, rash, headache, CNS disturbances, arthralgia, myalgia, gynaecomastia, alopoecia, blood dyscrasias, nephritis, hepatitis, pancreatitis, granulocytopenia, hypersensitivity reactions.

Pregnancy category ::
Pregnancy category

2

Drug Mode of Action ::  

Cimetidine competitively inhibits histamine at H2-receptors of the gastric parietal cells resulting in decreased gastric acid secretion, gastric volume and hydrogen ion concentration. It is also used in patients w/ pancreatic insufficiency to reduce the breakdown of pancreatic enzyme supplements.

Drug Interactions ::

Reduces absorption of dasatinib, ketoconazole, itraconazole and posaconazole. May increase serum levels of phenytoin, theophylline, lidocaine, hydroxyzine and oral anticoagulants. Absorption may be reduced by antacids. Decreased bioavailability w/ metoclopramide, sucralfate or propantheline. May potentiate the myelosuppressive effects (e.g. agranulocytosis, neutropenia) of myelosuppressive drugs (e.g. antimetabolites, alkylating agents) or therapies (e.g. radiation).

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.

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