The Brand Name PRILACE Has Generic Salt :: Ramipril 

PRILACE  Is From Company Cipla Priced :: Rs. 55.00/92.00

PRILACE have Ramipril is comes under Sub class Anti Hypertensives of  Main Class Cardiovascular System

Main Medicine Class:: Cardiovascular System  Sub Medicine Class :: Anti Hypertensives 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Ramipril  TAB  Rs. 55.00/92.00  10-Oct
Brand Name Company / Manufacturers Strength Unit Price / 10-Oct
 PRILACE  Cipla  2.5/5;MG  10-Oct Rs. 55.00/92.00

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Cipla :: PRILACE  Ramipril  Cardiovascular System Anti Hypertensives

Indications for Drugs ::

Congestive heart failure, MI, HTN, CV events, Stroke

Drug Dose ::

Adult: PO HTN Initial: 1.25 mg at bedtime. Maintenance: 2.5-5 mg/day as a single dose, up to 10 mg/day if needed. Heart failure Initial: 1.25 mg once daily. Max: 10 mg/day. MI Start 3-10 days after infarction. Initial: 2.5 mg twice daily after 2 days, then 5 mg twice daily. Maintenance: 2.5-5 mg twice daily. Prophylaxis of CV events in high-risk patients Initial: 2.5 mg once daily for 1 wk, then increased if tolerated to 5 mg once daily for 3 wk, then maintenance: 10 mg once daily. Renal impairment: CrCl (ml/min) 10-30 Initially, 1.25 mg/day. Max: 5 mg/day. 30-60 Not necessary to adjust the initial dose. Max: 5 mg/day. Hepatic impairment: Max: 2.5 mg/day.

Contraindication ::

Hypersensitivity, bilateral renal artery stenosis, or a single kidney with unilateral renal artery stenosis. Aortic stenosis or outflow tract obstruction. Pregnancy and lactation.

Drug Precautions ::

Renal impairment, hypovolaemia, hyperkalaemia, valvular stenosis; before, during or immediately after anaesthesia. Severe resistant hypertension, elderly, peripheral vascular disease or generalised atherosclerosis. Monitor renal function before and during treatment. Use with caution in patients with history of idiopathic or hereditary angioedema. Regular monitoring of WBC in patients with vascular collagen disorders is recommended.

Drug Side Effects ::

Nausea, vomiting, diarrhoea, dizziness, fatigue, headache, abdominal pain, cough. Rarely symptomatic hypotension. Angioneurotic oedema of face, lips, tongue, glottis and larynx, syncope, renal impairment, hypersensitivity reactions. Potentially Fatal: Severe hypotension and renal failure, angioedema.

Pregnancy category ::
Pregnancy category


Drug Mode of Action ::  

Ramipril, a prodrug of ramiprilat, competitively inhibits ACE from converting angiotensin I to angiotensin II (a potent vasoconstrictor) resulting in increased plasma renin activity and reduced aldosterone (a hormone that causes water and Na retention) secretion. This promotes vasodilation thus producing a hypotensive effect and a beneficial effect in CHF.

Drug Interactions ::

May enhance hypotensive effect w/ diuretics and other antihypertensives. May increase risk of renal function deterioration w/ NSAIDs. May increase serum levels and toxicity of lithum. May increase hyperkalaemic effect w/ K-sparing diuretics and supplements. Potentially Fatal: Concomitant use w/ aliskiren aliskiren may increase the risk of hyperkalaemia, hypotension and nephrotoxicity in patients w/ diabetes or renal impairment


Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.

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