Cefditoren

Details About Generic Salt ::  Cefditoren 

Main Medicine Class:: Anti Infectives   Sub Medicine Class ::  Cephalosporins

13B. CEPHALOSPORINS in 13. ANTI-INFECTIVES
CEFDITOREN
THIRD-GENERATION CEPHALOSPORIN | ANTI-INFECTIVE
PK: D: 9.3 ± 1.6 L M: Hepatic E: Urine

Indications & Dose: ACUTE BACTERIAL EXACERBATION OF CHRONIC BRONCHITIS PO Adult 400mg BID 10 days Child >12 yr: Same as adult dose | COMMUNITY-ACQUIRED PNEUMONIA PO Adult 400mg BID 14 days Child >12 yr: Same as adult dose | PHARYNGITIS PO Adult 200mg BID 10 days Child >12 yr: Same as adult dose | SKIN STRUCTURE INFECT Uncomplicated PO Adult 200mg BID 10 days Child >12 yr: Same as adult dose | TONSILLITIS PO Adult 200mg BID 10 days Child >12 yr: Same as adult dose

Contra: Hypersensitivity, milk protein, carnitine deficiency

Precautions: Penicillin-sensitive patients, history of allergy, false positive Coombs’ test, false-positive reactions for glucose using copper-reduction reactions, false Jaffé method of measuring creatinine level, renal impairment

ADR: Serious: Blood disorders, hypersensitivity reactions, anaphylaxis, bleeding complications, hypoprothrombinemia, platelet dysfunction, nephrotoxicity, acute interstitial nephritis, hepatitis, transient increases in liver enzyme values, cholestatic jaundice, convulsions, CNS toxicity, overgrowth of non-susceptible organisms, thrombophlebitis, Others: Skin rashes, urticaria, eosinophilia, fever, nausea, vomiting, diarrhea, pain at inj site, local reactions

DDI: Serious Probenecid reduces drug renal excretion

Diet: With food

Monitor: Renal & hematological status, signs of anaphylaxis (first dose)

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