The Brand Name CHLOZ Has Generic Salt :: Chlorambucil 

CHLOZ  Is From Company Intas Priced :: Rs. 3300

CHLOZ have Chlorambucil is comes under Sub class Anti Neoplastic Agents of  Main Class Anti Neoplastic Agents

Main Medicine Class:: Anti Neoplastic Agents  Sub Medicine Class :: Anti Neoplastic Agents 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Chlorambucil  INJ  Rs. 3300  VIAL
Brand Name Company / Manufacturers Strength Unit Price / VIAL
 CHLOZ  Intas  5MG  VIAL Rs. 3300

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Intas :: CHLOZ  Chlorambucil  Anti Neoplastic Agents Anti Neoplastic Agents

Indications for Drugs ::

Lymphocytic leukemia, non-Hodgkin lymphoma, Waldenstrm macroglobulinemia, polycythemia vera, trophoblastic neoplasms, ovarian carcinoma, nephrotic syndrome, Hodgkin’s disease

Drug Dose ::

Adult: PO Hodgkin’s disease 200 mcg/kg/day. Maintenance: 30-100 mcg/kg/day. Non-Hodgkin’s lymphoma 100 mcg/kg/day. Maintenance: 30-100 mcg/kg/day. Chronic lymphocytic leukaemia 100-200 mcg/kg/day for 3-8 wk. Maintenance: 30-100 mcg/kg/day. Waldenstrom’s macroglobulinaemia Initial: 6-12 mg/day until leucopenia develops. Maintenance: 2-8 mg/day.

Contraindication ::

Hypersensitivity. Pregnancy and lactation. Porphyria.

Drug Precautions ::

Renal or hepatic dysfunction. Perform blood counts regularly. Seizure disorder, bone marrow suppression. Patient who has received radiation therapy, myelosuppressive drugs or has a depressed baseline leukocyte/platelet count within the previous 4 wk. Increased incidence of acute leukaemias and other secondary malignancies.

Drug Side Effects ::

Reversible progressive lymphocytopenia and neutropenia; GI disturbances; hepatotoxicity; skin rashes; peripheral neuropathy; central neurotoxicity including seizures; interstitial pneumonia, pulmonary fibrosis. High doses may produce azoospermia and amenorrhoea. Sterility when given to boys at or before puberty. Potentially Fatal: Severe bone marrow suppression, carcinogenic and human infertility.

Pregnancy category ::
Pregnancy category

4

Drug Mode of Action ::  

Chlorambucil interferes with DNA replication and RNA transcription by alkylation and cross-linking cellular DNA strands, thus leading to disruption of the nucleic acid function.

Drug Interactions ::

Impairs immune response to vaccines, possible infection after admin of live vaccines.

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
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