The Brand Name CILODOC Has Generic Salt :: Cilostazol
CILODOC Is From Company Lupin Priced :: Rs. 520
CILODOC have Cilostazol is comes under Sub class Drugs for Vascular disorder of Main Class Cardiovascular System
Main Medicine Class:: Cardiovascular System Sub Medicine Class :: Drugs for Vascular disorder
|Salt Name : OR Generic Name||Form||Price : MRP /Probable||Packing|
Indications for Drugs ::
Peripheral vascular disease, Intermittent claudication
Drug Dose ::
Adult: PO 100 mg twice daily.
Heart failure; known predisposition to bleeding; history of ventricular arrhythmias; QT interval prolongation; severe renal impairment; moderate to severe hepatic impairment.
Drug Precautions ::
Congestive heart disease. Concurrent therapy with clopidogrel has not been studied for safety or efficacy. Pregnancy and lactation.
Drug Side Effects ::
Headache, dizziness, palpitations, diarrhoea, abnormal stools; pain, infection; peripheral oedema, nausea, vomiting, other cardiac arrhythmias, chest pain, rhinitis, pharyngitis, ecchymosis and skin rash.
Pregnancy category ::
Drug Mode of Action ::
Cilostazol is a reversible, selective inhibitor of phosphodiesterase-III (PDE-III), thereby suppressing cyclic adenosine monophosphate (cAMP) degradation. Increase in cAMP in platelets and blood vessels leads to inhibition of platelet aggregation and vasodilation. Cilostazol also inhibits adenosine uptake into cells, which augments the cAMP-elevating effect of PDE-III inhibition.
Drug Interactions ::
Co-admin with drugs that affect CYP3A4 (erythromycin, other macrolides, diltiazem) or CYP2C19 (omeprazole) may influence the pharmacokinetics of cilostazol.