Article Contents ::
Details About Generic Salt :: Ivabradine
Main Medicine Class:: Cardiovascular System Sub Medicine Class :: Anti Anginals
| 4C. ANTI-ANGINALS in 4. CARDIOVASCULAR SYSTEM |
| IVABRADINE |
| SELECTIVE SINUS NODE IF INHIBITOR | ANTI-ANGINAL |
| PK: A: completely absorbed M: Hepatic E: urine & feces |
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Indications & Dose: ANGINA PECTORIS PO Adult Initially 5mg BID, may be increased to 7.5mg BID after 3 or 4wks, if HR falls <50 beats/min titrate dose to 2.5mg BID Elderly >75 yr: 2.5mg BID |
| Contra: Cardiogenic shock, severe hypotension, severe hepatic impairment, unstable angina
Precautions: severe renal impairment, history of retinitis pigmentosa, QT prolongers ADR: Serious: Luminous phenomena, hyperuricemia, bradycardia, arrhythmias, muscle cramps, Others: nausea, constipation, diarrhea, headache, dizziness, dyspnea, elevated blood-creatinine concentrations, eosinophilia, blurred vision DDI: Serious Rifampicin/Phenytoin decreases drug level, HIV protease inhibitors/Diltiazem/Nefazodone/Verdenafil increases drug level Diet: With food |