Article Contents ::
Details About Generic Salt :: Nateglinide
Main Medicine Class:: Endocrine,Steroid Hormones , Metabolic System Sub Medicine Class :: Insulin , Anti Diabetic drugs
| 8D. INSULIN & ANTI-DIABETIC DRUGS in 8. ENDOCRINE/STEROID HORMONES & METABOLIC SYSTEM |
| NATEGLINIDE |
| MEGLITINIDE DERIVATIVE | ANTI-DIABETIC |
| PK: A: Rapid D: 10L M: Hepatic E: Urine (83%)& feces (10%) |
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Indications & Dose: TYPE 2 DIABETES MELLITUS PO Adult Initially & MD 120mg TID, may be given alone/combination with metformin/thiazolidinedione |
| Contra: Hypersensitivity, DKA, type 1 DM
Precautions: Elderly, substitute insulin during intercurrent illness, malnourished patients, hepatic impairment ADR: Serious: Hypoglycemia, jaundice, hypersensitivity reactions, Others: headache, dizziness, pruritus, weight gain, arthropathy DDI: Serious Itraconazole/Fluconazole modestly increases drug levels Others Rifampicin decreases drug levels Diet: Before food (30 mins) Monitor: Glucose, HbA1c levels, weight & lipid profile |