Article Contents ::
Details About Generic Salt :: Nebivolol
Main Medicine Class:: Cardiovascular System Sub Medicine Class :: Anti Hypertensives
| 4D. ANTI-HYPERTENSIVES in 4. CARDIOVASCULAR SYSTEM |
| NEBIVOLOL |
| CARDIOSELECTIVE ß-BLOCKER | ANTI-HYPERTENSIVE |
| also comes under 4A. Drugs for Cardiac Failure & Shock in 4. Cardiovascular System |
| PK: A: Rapid M: Hepatic E: Urine & feces |
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Indications & Dose: HEART FAILURE PO Adult Initially 1.25mg/day, if tolerated double the dose q1-2wk max 10mg/day | HYPERTENSION PO Adult Initially 5mg/day, if no response increase dose after 2wk max 40mg/day Elderly >65 yr: Initially 2.5mg/day may be increased to 5mg/day if needed |
| Contra: pheochromocytoma, metabolic acidosis, cardiogenic shock, hypotension, severe peripheral arterial disease, second/third degree AV block, sinus bradycardia
Precautions: asthma, history of obstructive airways disease, first degree AV block ADR: Serious: peripheral edema, bradycardia, chest pain, arthralgia, myopathies, muscle cramps, blood disorders, hypoglycemia, changes in lipid levels, Others: headache, fatigue, dizziness, insomnia, rash, bronchospasm, dyspnea, paresthesia DDI: Serious GA potentiates hypnosis |