Famciclovir

Details About Generic Salt ::  Famciclovir 

Main Medicine Class:: Anti Infectives   Sub Medicine Class ::  Anti Virals (Non Retroviral)

13M. ANTI-VIRALS (NON RETROVIRAL) in 13. ANTI-INFECTIVES
FAMCICLOVIR
SYNTHETIC NUCLEOSIDE | ANTI-VIRAL
PK: A: Rapid D: 0.91-1.25 L/kg (Vd) M: Hepatic E: Urine (73%), feces (27%)

Indications & Dose: GENITAL HERPES SIMPLEX VIRUS INFECTION PO Adult Initial episode: 250mg TID 7-10 days (immunocompetent) | PO Adult 500mg BID 7 days or 5-10 days (HIV patients) | HERPES ZOSTER Acute PO Adult 500mg q8h 7 days | RECURRENT GENITAL HERPES SIMPLEX VIRUS INFECTION PO Adult 1g BID 1 day (immunocompetent) | RECURRENT HERPES LABIALIS PO Adult 1.5gm single dose initiate at first sign or symptom appear | SUPPRESSION OF RECURRENT EPISODES OF GENITAL HSV INFECT PO Adult 250mg BID up to 1 yr (immunocompetent)

Contra: Hypersensitivity

Precautions: Renal impairment

ADR: Serious: ARF, jaundice, increased transaminases, bilirubin, Others: headache, nausea, vomiting, dizziness, skin rash, pruritus, urticaria, somnolence, confusion, hallucinations, abdominal pain, fever

DDI: Serious Raloxifene inhibits drug metabolism, Probenecid reduces drug renal excretion & increases its levels

Diet: With/without food

Monitor: CBC

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