Myxedema coma Diagnosis and Treatment

Myxedema coma 

Myxedema coma Risk Factors

Myxedema coma DIAGNOSIS —

Myxedema coma Initial Lab Tests

  • •Primary hypothyroidism
  • •Central hypothyroidism:
    • Impaired TSH response to TRH
    • Serum free T4 decreased
    • TSH low
  • •Severe hypothyroidism:
    • Hyponatremia
    • Elevated CPK, LDH, AST
    • Elevated cholesterol
    • Anemia
  • •Subclinical hypothyroidism:
    • TSH elevated
    • Serum free T4 normal

Myxedema coma Treatment

  • LevothyroxineLevothyroxine. Read more ... »-single IV bolus 500 mcg loading dose then 100 mcg/day. Levothyroxine may be given by nasogastric tube as crushed tablets.
  • Patient is kept warm.
  • Hydrocortisone IV 50 mg 6 hrly is given. Broad spectrum antibiotics for infection. Hypertonic saline and IV glucose.

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69 − = 65