NISPAM 20ML 1G | MedicScientist :: Total Health Portal

The Brand Name NISPAM Has Generic Salt :: Pralidoxime 

NISPAM  Is From Company Neiss Priced :: Rs. 320

NISPAM have Pralidoxime is comes under Sub class Toxicity and Poison Management (Antidotes) of  Main Class Toxicity and Poison Management (Antidotes)

Main Medicine Class:: Toxicity and Poison Management (Antidotes)  Sub Medicine Class :: Toxicity and Poison Management (Antidotes) 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Pralidoxime  VIAL  Rs. 320  20ML
Brand Name Company / Manufacturers Strength Unit Price / 20ML
 NISPAM  Neiss  1G  20ML Rs. 320

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Neiss :: NISPAM  Pralidoxime  Toxicity and Poison Management (Antidotes) Toxicity and Poison Management (Antidotes)

Indications for Drugs ::

Organophosphorous poisoning

Drug Dose ::

Adult: IV/IM Used in combination w/ atropine. As Cl, iodide or mesilate: Upon atropinisation, administer 1-2 g, repeat dose after 1 hr, then 8-12 hrly if needed. Severe: 200-500 mg/hr via continuous infusion, titrate according to response. Max: 12 g/24 hr. Child: IV loading dose followed by continuous infusion 20-50 mg/kg/dose (not to exceed 2 g/dose) infused IV over 15-30 minutes Maintenance: 10-20 mg/kg/hr IV continuous infusion. IM administration <40 kg: 15 mg/kg/dose IM x3 doses 40 kg or greater: Administer as in adults; 600 mg/dose IM x3 doses. Contraindication ::

Carbamate pesticide poisoning, hypersensitivity.

Drug Precautions ::

Renal dysfunction, myasthenia gravis. Atropinisation may occur faster when atropine and pralidoxime are used together. Pregnancy, lactation.

Drug Side Effects ::

Drowsiness, dizziness, visual disturbances, nausea, tachycardia, headache, hyperventilation and muscle weakness. Potentially Fatal: Rapid admin causes tachycardia, laryngospasm and rigidity. Large doses cause neuromuscular blockade.

Pregnancy category ::
Pregnancy category

3

Drug Mode of Action ::  

Pralidoxime reactivates cholinesterase outside the CNS which has been inactivated by phosphorylation due to organophosphate pesticide exposure-resulting. This leads to the destruction of acetylcholine at the neuromuscular junction thus relieving muscle paralysis. It also removes the phosphyl group from the active site of inactivated enzyme which is dependent on the nature of the phosphyl group.

Drug Interactions ::

0

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.