ONTOP SILDENAFIL CITRATE 4 50MG

The Brand Name ONTOP SILDENAFIL CITRATE Has Generic Salt :: Sildenafil 

ONTOP SILDENAFIL CITRATE  Is From Company ONTOP Priced :: Rs. 80

ONTOP SILDENAFIL CITRATE have Sildenafil is comes under Sub class #N/A of  Main Class #N/A

Main Medicine Class:: #N/A  Sub Medicine Class :: #N/A 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Sildenafil    Rs. 80  4
Brand Name Company / Manufacturers Strength Unit Price / 4
 ONTOP SILDENAFIL CITRATE  ONTOP  50MG  4 Rs. 80

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From ONTOP :: ONTOP SILDENAFIL CITRATE  Sildenafil  #N/A #N/A

Indications for Drugs ::

Altitude sickness, Pulmonary arterial hypertension, Erectile dysfunction

Drug Dose ::

Oral Erectile dysfunction Adult: 50 mg about 1 hr before sexual intercourse. May adjust dose depending on penile response. Max: 100 mg/dose and not to be taken > once in 24 hr. Elderly: >65 yr: Lower initial dose at 25 mg. Renal impairment: CrCl (ml/min) <30 initially, 25 mg. hepatic impairment: mg. Contraindication ::

Hypersensitivity. Patients concurrently or intermittently using organic nitrates in any form.

Drug Precautions ::

Caution when used in patients with anatomical deformation of penis or conditions that may predispose them to priapism (e.g. sickle cell anaemia, myeloma, or leukaemia). Mild, transient, dose-related impairment of colour discrimination (blue/green) may occur. Hepatic or severe renal impairment, bleeding disorders, active peptic ulceration, hypotension, recent history of stroke, MI, arrhythmias, unstable angina, heart failure or retinal disorders. May cause sudden loss or decrease in hearing.

Drug Side Effects ::

Headache, flushing, respiratory tract infection, angina pectoris, AV block, migraine, syncope, tachycardia, postural hypotension, MI, cerebral thrombosis, cardiac arrest, paraesthesia, tremor, depression, herpes simplex, skin ulcer, oesophagitis, abnormal LFT, rectal haemorrhage, hypoglycaemic reaction, arthritis, deafness, retinal vascular disease, photosensitivity, accidental fall.

Pregnancy category ::
Pregnancy category

2

Drug Mode of Action ::  

Sildenafil inhibits phosphodiesterase type-5 (PDE5) which is responsible for cGMP degradation in the corpus cavernosum. Inhibition of PDE5 increases cGMP levels in the corpus cavernosum which results in smooth muscle relaxation and inflow of blood to the corpus cavernosum.

Drug Interactions ::

Inhibitors of CYP3A4 such as cimetidine and erythromycin are likely to reduce sildenafil clearance. CYP3A4 inducers such as rifampicin may decrease the plasma concentrations of sildenafil. Symptomatic hypotension when used with ?-blockers. Plasma concentrations are increased by ritonavir. Potentially Fatal: May potentiate hypotensive effects of of organic nitrates and nicorandil.

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
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