Details About Overdose or Poisoning Generic Salt :: Fomepizole 4 Methylpyrazole, 4 MP Fomepizole (4-Methylpyrazole, 4-MP) Drug Pharmacology :: I. Pharmacology./b> Fomepizole(4-methylpyrazole) is a potent competitive inhibitor of alcoholdehydrogenase, the first enzyme in the metabolism of ethanol and otheralcohols. Fomepizole can prevent the formation of toxic metabolitesafter methanol or ethylene glycol...
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Details About Overdose or Poisoning Generic Salt :: Potassium Potassium Drug Pharmacology :: I. Pharmacology. Potassiumis the primary intracellular cation, which is essential for maintenanceof acid-base balance, intracellular tonicity, transmission of nerveimpulses, contraction of cardiac, skeletal, and smooth muscle, andmaintenance of normal renal function (and ability to alkalinize urine).Potassium also acts as...
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Details About Overdose or Poisoning Generic Salt :: Vitamin K1, Phytonadione Vitamin K1 (Phytonadione) Drug Pharmacology :: I. Pharmacology. Vitamin K1 is an essential cofactor in the hepatic synthesis of coagulation factors II, VII, IX, and X. In adequate doses, vitamin K1 reverses the inhibitory effects of coumarin and indanedione derivatives on...
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Details About Overdose or Poisoning Generic Salt :: Tetanus Toxoid And Immune Globulin Tetanus Toxoid and Immune Globulin Drug Pharmacology :: I. Pharmacology. Tetanus is caused by tetanospasmin, a protein toxin produced by Clostridium tetani (see Tetanus). Tetanus toxoiduses modified tetanospasmin, which has been made nontoxic but stillretains the ability to...
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Details About Overdose or Poisoning Generic Salt :: Antivenom, Micrurus Fulvius Coral Snake, And Exotic Antivenoms Antivenom, Micrurus Fulvius (Coral Snake), and Exotic Antivenoms Drug Pharmacology :: I. Pharmacology. To produce the antivenom for North American coral snake bites, horses are hyperimmunized with venom from Micrurus fulvius,the eastern coral snake. The lyophilized...
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Details About Overdose or Poisoning Generic Salt :: Benztropine Benztropine Drug Pharmacology :: I. Pharmacology. Benztropineis an antimuscarinic agent with pharmacologic activity similar to thatof atropine. The drug also exhibits antihistaminic properties.Benztropine is used for the treatment of parkinsonism and the controlof extrapyramidal side effects associated with neuroleptic use. Drug Indications ::...
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Details About Overdose or Poisoning Generic Salt :: Leucovorin Calcium Leucovorin Calcium Drug Pharmacology :: I. Pharmacology. Leucovorin(folinic acid or citrovorum factor) is a metabolically functional formof folic acid. Unlike folic acid, leucovorin does not require reductionby dihydrofolate reductase, and therefore it can participate directlyin the one-carbon transfer reactions necessary for purine...
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Details About Overdose or Poisoning Generic Salt :: Diazoxide Diazoxide Drug Pharmacology :: I. Pharmacology./b> Diazoxide,a nondiuretic thiazide, is a direct arterial vasodilator that formerlywas used to treat severe hypertension. Heart rate and cardiac outputincrease owing to a reflex response to decreased peripheral vascularresistance. The duration of the hypotensive effect ranges...
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Details About Overdose or Poisoning Generic Salt :: Epinephrine Epinephrine Drug Pharmacology :: I. Pharmacology. Epinephrineis an endogenous catecholamine with alpha- and beta-adrenergic agonistproperties that is used primarily in emergency situations to treatanaphylaxis or cardiac arrest. Beneficial effects include inhibition ofhistamine release from mast cells and basophils, bronchodilation,positive inotropic effects, and peripheral...
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Details About Overdose or Poisoning Generic Salt :: Norepinephrine Norepinephrine Drug Pharmacology :: I. Pharmacology. Norepinephrineis an endogenous catecholamine that stimulates mainly alpha-adrenergicreceptors. It is used primarily as a vasopressor to increase systemicvascular resistance and venous return to the heart. Norepinephrine isalso a weak beta-1-adrenergic receptor agonist, and it may increaseheart rate...
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