The Brand Name PYROLATE Has Generic Salt :: Glycopyrrolate
PYROLATE Is From Company Neon Priced :: Rs. 12.60/86.40
PYROLATE have Glycopyrrolate is comes under Sub class GERD, of Main Class Gastrointestinal System
Main Medicine Class:: Gastrointestinal System Sub Medicine Class :: GERD,
|Salt Name : OR Generic Name||Form||Price : MRP /Probable||Packing|
Indications for Drugs ::
Hyperhidrosis, Peptic ulcer, Anesthesia, Sialorrhea, Cerebral palsy, Reversal of neuromuscular blockade
Drug Dose ::
Parenteral Reduction of secretions Adult: Preoperative: 4 mcg/kg via IM admin 30-60 minutes before procedure. Intraoperative: 0.1 mg via IV admin, repeat at 2-3 minute intervals when needed. Max: 400 mcg/dose. Child: Preoperative: IM admin: <2 yr: 4-9 mcg>2 yr: 4 mcg/kg, dose to be given 30-60 minutes before procedure. Intraoperative: IV admin: 4 mcg/kg (Max: 0.1 mg); repeat at 2-3-minute intervals as needed. Max Dosage: Adult: 400 mcg/dose. Child >1 mth: 200 mcg/dose. Intravenous Reversal of neuromuscular blockade Adult: 200 mcg for each 1 mg of neostigmine or 5 mg of pyridostigmine. Alternatively, 5-15 mcg/kg with 50 mcg/kg neostigmine with 25-70 mcg/kg of neostigmine or 0.1-0.3 mg/kg of pyridostigmine. Child: 10 mcg/kg with 50 mcg/kg neostigmine. Parenteral Peptic ulcer Adult: 0.1-0.2 mg 3-4 times daily via IM/IV admin.
Hypersensitivity. Glaucoma; obstructive uropathy; obstructive GI diseases; intestinal atony; paralytic ileus; pyloric stenosis; myasthenia gravis. Unstable CV status in acute haemorrhage. Injectable not recommended in new borns <1 mth if benzyl alcohol is present in the preparation. Drug Precautions ::
Pregnancy, lactation. CV disease, hyperthyroidism, hepatic or renal impairment. Enlarged prostate, diarrhoea, fever. May cause ileus or megacolon in patients with ulcerative colitis. Children and elderly.
Drug Side Effects ::
Xerostomia; loss of taste, nausea, vomiting, constipation, reduced sweating; urinary hesitancy and retention; blurred vision; cycloplegia; increased ocular tension; tachycardia; palpitation; headache, anxiety, bloated feeling, impotence, skin reactions. Potentially Fatal: Severe anaphylaxis.
Pregnancy category ::
Drug Mode of Action ::
Glycopyrronium bromide is a quarternary ammonium antimuscarinic. It blocks acetylcholine at parasympathomimetic sites and induces smooth muscle relaxation. It also reduces gastric acid secretions and controls pharyngeal, tracheal and bronchial secretions. It antagonises muscarinic symptoms such as bronchorrhoea, bronchospasm, bradycardia and intestinal hypermotility induced by anticholinesterases.
Drug Interactions ::