Details About Generic Salt ::  Basilixi

Main Medicine Class:: Immunosuppressive   

Powder for injection: 20 mg
Class: Immunosuppressive


Drugs Class ::

 Action Blocks the interleukin-2 receptor a-chain, which is a critical pathway in allograft rejection.

Indications for Drugs ::

 Indications Prophylaxis of acute organ rejection in patients receiving renal transplantation when used as part of an immunosuppressive regimen that includes cyclosporine and corticosteroids. Prophylaxis of solid organ rejection.

Drug Dose ::


ADULTS: IV 20 mg within 2 hr prior to transplantation surgery, followed by 20 mg 4 days after transplantation.

CHILDREN (2 to 15 yr): IV 12 mg/m2 (max 20 mg/m2) within 2 hr prior to transplantation surgery, followed by same dose 4 days after transplantation.

Contraindication ::

 Contraindications Standard considerations.

Drug Precautions ::


Pregnancy: Category B. Lactation: Undetermined. Children: Safety and efficacy not established. Elderly: Safety and efficacy not established. Opportunistic Infections/Lymphoproliferative Disorders: Risk of developing these complications may be increased. Hypersensitivity: Although not reported, can occur following administration of proteins.


Drug Side Effects ::

 Adverse Reactions

CARDIOVASCULAR: Hypertension; hypotension; angina pectoris; cardiac failure; abnormal heart sounds; arrhythmia; atrial fibrillation; tachycardia; vascular disorder. RESPIRATORY: Dyspnea; upper respiratory tract infection; coughing; rhinitis; pharyngitis; bronchitis; bronchospasm; abnormal chest sounds; pneumonia; pulmonary disorder; pulmonary edema. CNS: Headache; tremor; dizziness; insomnia; hypoesthesia; neuropathy; paresthesia; agitation; anxiety; depression; fatigue; malaise. EENT: Cataracts; conjunctivitis; abnormal vision; sinusitis. GI: Constipation; nausea; diarrhea; abdominal pain; vomiting; dyspepsia; moniliasis; enlarged abdomen; flatulence; gastroenteritis; GI hemorrhage; gum hyperplasia; melena; esophagitis; ulcerative stomatitis. GU: Dysuria; urinary tract infection; increased nonprotein nitrogen; impotence; genital edema; albuminuria; bladder disorder; hematuria; frequent micturition; oliguria; abnormal renal function; renal tubular necrosis; ureteral disorder; urinary retention. HEMATOLOGIC: Anemia; hemorrhage; purpura; thrombocytopenia; thrombosis; polycythemia. DERMATOLOGIC: Acne; surgical wound complications; cyst; herpes simplex; herpes zoster; hypertrichosis; pruritus; rash; skin ulceration. METABOLIC: Hyperkalemia; hypokalemia; hyperglycemia; hypoglycemia; hyperuricemia; hypomagnesemia; hypophosphatemia; hypocalcemia; hypercholesterolemia; hyperlipidemia; hyperproteinemia; weight gain; acidosis; dehydration; diabetes mellitus; fluid overload. OTHER: Pain; chest pain; leg pain; back pain; asthenia; arthralgia; arthropathy; bone fracture; cramps; hernia; myalgia; hematoma; edema; peripheral edema; facial edema.

Drug Mode of Action ::  

 Action Blocks the interleukin-2 receptor a-chain, which is a critical pathway in allograft rejection.

Drug Interactions ::


None well documented.

No data available; do not add or infuse other drugs simultaneously through the same IV line.

Drug Assesment ::


  • Obtain patient history, including drug history and any known allergies.
  • Monitor for signs of hypersensitivity. Have medications for the treatment of severe hypersensitivity available for immediate use.
  • Discontinue infusion immediately if signs of hypersensitivity are present; keep IV line open, follow institution emergency protocol, and notify health care provider
  • Monitor for adverse reactions.
  • Maintain sterility and monitor infusion site, IV rate, and patient during infusion.

Drug Storage/Management ::


  • Store lysophilized basiliximab under refrigerated conditions at 2° to 8°C (36° to 46°F). The reconstituted solution can be refrigerated for 24 hr or at room temperature for 4 hr. Discard reconstituted solution if not used in 24 hr. Use the reconstituted solution immediately and dilute as directed
  • Inspect the bag for particulate matter or solution discoloration, and if present do not use.
  • Administer with care to assure sterility as the solution contains no antimicrobial preservatives.
  • Do not administer or add other drug substances to the same bag or infuse simultaneously through the same IV line.
  • Do not shake solution; invert bag gently to avoid foaming.
  • Administer diluted solution through central or peripheral IV only over 20 to 30 min using sterile technique.

Drug Notes ::

 Patient/Family Education

  • Instruct patient or family to monitor for signs and symptoms of adverse events and report immediately to primary health care provider.
  • Instruct family or patient to monitor for signs and symptoms of infections and transplant rejection including fever, pain, and urinary tract infections. Report these symptoms immediately to primary care provider.
  • Advise women to notify health care provider immediately if pregnant, planning to become pregnant, or planning to breastfeed.
  • Instruct women of childbearing potential to use effective contraception before beginning therapy, during therapy, and for 2 mo after the completion of therapy.
  • Nursing mothers should discontinue nursing prior to using the drug.
  • Stress the importance of regular exams and laboratory work.
  • Encourage patient to comply with the treatment regimen.


Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.


One of the 1st in India.High Quality Generic Medicine Portal Android Application for Online Oreder & Information.

For More Join Our Membership and Get Additional 25% off on Meds, also get MLM Benefits to get a permanent earning source.

Join Membership How to Search Medicine
Android App

We would like to keep you updated with special notifications.