Details About Generic Salt ::  Galantam

Main Medicine Class:: Cholinesterase inhibitor   

Reminyl
Class: Cholinesterase inhibitor

 

Drugs Class ::

 Action May enhance cholinergic function by increasing acetylcholine.

Indications for Drugs ::

 Indications Treatment of mild to moderate dementia of the Alzheimer type.

Drug Dose ::

 Route/Dosage

ADULTS: PO 4 mg bid. May increase to 8 mg bid after 4 wk. A further increase to 12 mg bid may be attempted after a minimum of 4 wk at previous dose.

Contraindication ::

 Contraindications Standard considerations.

Drug Precautions ::

 Precautions

Pregnancy: Category B. Lactation: Undetermined. Children: Safety and efficacy not established. Concomitant medical conditions: As a result of increased cholinergic activity, other organ systems may be affected, possibly leading to bradycardia, obstructed bladder outflow, increased gastric acid secretion, or bronchoconstriction. Use with caution in patients susceptible to these effects. Hepatic or renal impairment: Use with caution in patients with moderately impaired function; not recommended in severe impairment.

PATIENT CARE CONSIDERATIONS


Drug Side Effects ::

 Adverse Reactions

cardiovascular Syncope; bradycardia; chest pain; hypertension. CNS: Dizziness; fatigue; headache; tremor; depression; insomnia; somnolence; agitation; confusion; anxiety; hallucinations. DERM: Purpura. GI: Nausea; vomiting; anorexia; diarrhea; abdominal pain; dyspepsia; constipation; flatulence. GU UTI; hematuria; urinary incontinence. HEMATOLOGIC Anemia. META: Weight decrease. RESPIRATORY Rhinitis; upper respiratory tract infection; bronchitis; coughing. OTHER: Injury; back pain; peripheral edema; asthenia; falling.

Drug Mode of Action ::  

 Action May enhance cholinergic function by increasing acetylcholine.

Drug Interactions ::

 Interactions

Bethanechol, succinylcholine: May act synergistically with galantamine. Erythromycin; ketoconazole; paroxetine: May elevate galantamine levels, increasing the risk of side effects.

Drug Assesment ::

 Assessment/Interventions

  • Obtain patient history, including drug history and any known allergies.
  • Note current cardiac, GI, GU, or pulmonary conditions and history of liver disease or renal disease.
  • Evaluate patient’s mental status and function prior to initiation of therapy.
  • Monitor patient for signs of improvement after therapy is started.
  • Monitor patient for side effects of drug. Report any to physician.
OVERDOSAGE: SIGNS & SYMPTOMS
  Cholinergic crisis (eg, severe nausea, vomiting, salivation, sweating, bradycardia, hypotension, respiratory depression, muscle weakness, collapse, convulsions)

Drug Storage/Management ::

 Administration/Storage

  • Administer bid, preferably with morning and evening meal.
  • Store at controlled room temperature (59° to 86°F). Keep container tightly closed.

Drug Notes ::

 Patient/Family Education

  • Explain name, dose, action, and potential side effects of drug.
  • Advise patient, family or caregiver that this drug does not alter the Alzheimer process and that the effectiveness of the medication may lessen over time.
  • Advise patient or caregiver that medication is taken bid, preferably with the morning and evening meal.
  • Advise patient or caregiver that medication is started at a low dose and gradually increased (no more often than every 4 wk) as tolerated.
  • Caution patient or caregiver that if medication has been stopped for several days or longer that the medication must be restarted at the lowest dose and gradually increased to the current dose.
  • Advise patient or caregiver that nausea and vomiting are the most common side effects and that taking the medication with food and ensuring adequate fluid intake reduces these side effects. If nausea and vomiting become a problem, the patient or caregiver should inform the prescribing physician.
  • Advise patient, family, or caregiver to not discontinue the drug or change the dose unless advised to do so by the physician.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.

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