Details About Generic Salt ::  Terbutal

Main Medicine Class:: Bronchodilator,Sympathomimetic   

(ter-BYOO-tuh-leen SULL-fate)
Brethaire, Brethine, Bricanyl
Class: Bronchodilator/Sympathomimetic


Drugs Class ::

 Action Produces bronchodilation by relaxing bronchial smooth muscle through beta2-receptor stimulation.

Indications for Drugs ::

 Indications Treatment of reversible bronchospasm associated with asthma, bronchitis and emphysema. unlabeled use (S): Inhibits premature labor.

Drug Dose ::


ADULTS & CHILDREN ³ 12 YR: Inhalation 2 inhalations (separated by 60 sec interval) q 4–6 hr. Do not repeat more than q 4 hr. ADULTS & CHILDREN ³ 15 YR: PO 2.5–5 mg at 6 hr intervals, 3 times per day during waking hours. Do not exceed 15 mg in 24 hr. CHILDREN 12–15 YR: PO 2.5 mg tid. Do not exceed 7.5 mg in 24 hr. SC 0.25 mg given in lateral deltoid area. May repeat in 15–30 min. Do not exceed 0.5 mg in 4 hr.

Premature Labor Inhibition

ADULTS: IV 10–80 mcg/min for 4 hr has shown some success. Maintenance: PO 2.5 mg q 4–6 hr.

Contraindication ::

 Contraindications Cardiac arrhythmias associated with tachycardia.

Drug Precautions ::


Pregnancy: Category B. Lactation: Excreted in breast milk. Labor and delivery: May inhibit uterine contractions and delay preterm labor. Children: Safety and efficacy in children < 12 years not established. Elderly: Lower doses may be required. Cardiovascular effects: Toxic symptoms in patients with cardiovascular disorders may occur. CNS effects: CNS stimulation may occur; use cautiously in patients with history of seizures or hyperthyroidism. Carcinogenesis: A significant increase in the incidence of leiomyomas of the mesovarium and ovarian cysts has been demonstrated. Diabetes: Dosage adjustment of insulin or oral hypoglycemic agent may be required. Excessive use: Paradoxical bronchospasm and cardiac arrest have been associated with excessive inhalant use. Hypersensitivity: Hypersensitivity (allergic) reactions can occur after administration. Hypokalemia: Decreases in potassium levels have occurred. Tolerance: If previously effective dose fails to provide relief, therapy may need to be reassessed.


Drug Side Effects ::

 Adverse Reactions

CV: Palpitations; tachycardia; chest discomfort or pain; arrhythmias; blood pressure changes/hypertension. CNS: Stimulation; tremor; dizziness; nervousness; drowsiness; headache; weakness. GI: Nausea; vomiting; GI distress. HEPA: Elevated liver enzymes. META: Hypokalemia (with high doses). RESP: Dyspnea. OTHER: Flushing; sweating; muscle cramps; hypersensitivity vasculitis; ECG changes (eg, sinus pause, atrial premature beats, AV block, ventricular premature beats, ST-T-wave depression, T-wave inversion, sinus bradycardia, atrial escape beat with aberrant conduction); increased heart rate; muscle cramps; central stimulations; pain at injection site; elevations in liver enzymes; seizures; hypersensitivity vasculitis.

Drug Mode of Action ::  

 Action Produces bronchodilation by relaxing bronchial smooth muscle through beta2-receptor stimulation.

Drug Interactions ::


Beta-blockers: Block bronchodilator effect of terbutaline. MAO inhibitors: Hypertension may occur. Tricyclic antidepressants: Cardiovascular effects of terbutaline may be enhanced.

Drug Assesment ::


  • Obtain patient history, including drug history and any known allergies.
  • Be alert for drug tolerance, which may occur with long-term use.
  Tremor, palpitations, increased heart rate, decreased blood pressure, seizures, hypokalemia, muscle cramps, headache, hyperglycemia

Drug Storage/Management ::


  • For IV administration, obtain baseline potassium level prior to administration and place patient on cardiac monitor to assess for tachycardia or arrhythmias. Toxic symptoms have been documented in patients with cardiovascular disorders.
  • Do not allow patient to use inhaler form of medication more than 6 times/day.
  • Limit subcutaneous doses to no more than 0.5 mg in 4 hours.
  • For patients who are also using steroid inhaler, make sure that terbutaline is used first and 5 min elapse before steroid inhaler is used.
  • Do not use medication if discolored.
  • Store at room temperature. Protect from light.

Drug Notes ::

 Patient/Family Education

  • Instruct patient on proper technique for use of inhalers and evaluate return demonstration.
  • Demonstrate use of spacer or peak flow meter if prescribed.
  • Caution patient not to use inhaler form of medication more than 6 times/day.
  • Advise patient to take tablets with food to avoid GI upset.
  • Inform patient that the drug can stop working over time. If this is noted or if the inhalation makes breathing worse, the physician should be notified at once.
  • Instruct patient to report these symptoms to physician: Chest pain, dizziness or headache or persisting symptoms of asthma.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.


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