Details About Generic Salt ::  Trimetho

Main Medicine Class:: Antiemetic and antivertigo,anticholinergic   

(try-meth-oh-BEN-zuh-mide HIGH-droe-KLOR-ide)
Arrestin, T-Gen, Tebamide, Ticon, Tigan, Tiject-20, Trimazide
Class: Antiemetic and antivertigo/anticholinergic


Drugs Class ::

 Action Believed to directly affect medullary chemoreceptor trigger zone to inhibit nausea.

Indications for Drugs ::

 Indications Prevention and treatment of nausea and vomiting.

Drug Dose ::


ADULTS: PO 250 mg tid-qid. PR 200 mg tid-qid. IM 200 mg tid-qid. CHILDREN 14–41 KG: PO 100–200 mg tid-qid. PR 100–200 mg tid-qid. CHILDREN < 14 KG: PR 100 mg tid-qid.

Contraindication ::

 Contraindications Hypersensitivity to benzocaine or other local anesthetics. Suppositories contraindicated in neonates or premature infants; parenteral use contraindicated in children.

Drug Precautions ::


Pregnancy: Safety not established. Lactation: Undetermined. Hypersensitivity: Has been reported; discontinue use of drug at first signs of sensitivity.


Drug Side Effects ::

 Adverse Reactions

CV: Hypotension (after injection). CNS: Mood depression; disorientation; headache; drowsiness; opisthotonos; izziness; seizures; coma; Parkinson-like symptoms. EENT: Blurred vision. GI: Diarrhea. HEMA: Blood dyscrasias. HEPA: Jaundice. OTHER: Local pain, burning, stinging, redness and swelling (after injection); ypersensitivity reactions; muscle cramps.

Drug Mode of Action ::  

 Action Believed to directly affect medullary chemoreceptor trigger zone to inhibit nausea.

Drug Interactions ::

 Interactions None well documented.

Drug Assesment ::


  • Obtain patient history, including drug history and any known allergies.
  • Assess bowel sounds and severity of nausea and vomiting.
  • Implement safety precautions, particularly during initial therapy until individual response is determined.
  • Implement general comfort measures.
  • Monitor response to therapy.
  • Monitor I&O.
  • Monitor vital signs, particularly BP.
  • Monitor for potential side effects, particularly drowsiness and hypotension.

Drug Storage/Management ::


  • Do not use oral route with vomiting.
  • If necessary, open capsule and mix with food or liquids for administration.
  • Use Z-track technique for IM administration.
  • Avoid exposure to light; store at room temperature.
  • Avoid freezing injectable.

Drug Notes ::

 Patient/Family Education

  • Instruct patient that when used for motion sickness, medication should be taken 30 min before exposure to motion.
  • Advise patient to report these symptoms to physician: dizziness, yellowing of skin or eyes, muscle cramps or abnormal movements.
  • Instruct patient to avoid intake of alcoholic beverages or other CNS depressants.
  • Advise patient that drug may cause drowsiness or dizziness and to use caution while driving or performing tasks requiring mental alertness.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.


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