Details About Generic Salt ::  Triptore

Main Medicine Class::    

(trip-toe-REL-in)
Trelstar Depot
Microgranules for injection, lyophilized
Equivalent to 3.75 mg triptorelin peptide base
Trelstar LA
Microgranules for injection, lyophilized
Equivalent to 11.25 mg triptorelin peptide base
Class: Gonadotropin-releasing hormone

 

Drugs Class ::

 Action Synthetic analog of gonadotropin-releasing hormone (GnRH) that acts as potent inhibitor of gonadotropin secretion.

Indications for Drugs ::

 Indications Palliative treatment of advanced prostate cancer and as an alternative treatment for prostate cancer when orchiectomy or estrogen administration are not indicated or unacceptable to the patient.

Drug Dose ::

 Route/Dosage

Trelstar Depot Adults IM 3.75 mg in a depot formulation administered as a single monthly injection.

Trestar LA Adults IM 11.25 mg in long-acting formulation administered q 84 days.

Contraindication ::

 Contraindications Hypersensitivity to triptorelin or any component of product; other gonadotropin-releasing hormone agonists; pregnancy.

Drug Precautions ::

 Precautions

Pregnancy: Category X. Lactation: Undetermined. Children: Safety and efficacy not established. Hypersensitivity: Anaphylactic reactions have been reported. Special risk patients: Spinal cord compression or renal impairment have been reported. Worsening signs and symptoms: Drug initially causes transient increase in testosterone, which may lead to worsening of signs and symptoms of prostate cancer (eg, bone pain) during first few weeks of treatment.

Drug Side Effects ::

 Adverse Reactions

CARDIOVASCULAR: Hypertension. CNS: Dizziness; emotional lability; headache; insomnia. GI: Diarrhea; vomiting. GU: Bladder outlet obstruction; hematuria; impotence; urinary retention; UTI. HEMATOLOGIC: Anemia. OTHER: Bone pain; fatigue; hot flashes; leg pain; injection site pain; pain; pruritus; skeletal pain; spinal cord compression.

Drug Mode of Action ::  

 Action Synthetic analog of gonadotropin-releasing hormone (GnRH) that acts as potent inhibitor of gonadotropin secretion.

Drug Interactions ::

 Interactions

Hyperprolactinemic drugs: Do not administer concurrently with triptorelin.

Drug Assesment ::

 Precautions

Pregnancy: Category X. Lactation: Undetermined. Children: Safety and efficacy not established. Hypersensitivity: Anaphylactic reactions have been reported. Special risk patients: Spinal cord compression or renal impairment have been reported. Worsening signs and symptoms: Drug initially causes transient increase in testosterone, which may lead to worsening of signs and symptoms of prostate cancer (eg, bone pain) during first few weeks of treatment.

Drug Storage/Management ::

 Precautions

Pregnancy: Category X. Lactation: Undetermined. Children: Safety and efficacy not established. Hypersensitivity: Anaphylactic reactions have been reported. Special risk patients: Spinal cord compression or renal impairment have been reported. Worsening signs and symptoms: Drug initially causes transient increase in testosterone, which may lead to worsening of signs and symptoms of prostate cancer (eg, bone pain) during first few weeks of treatment.

Drug Notes ::

 Precautions

Pregnancy: Category X. Lactation: Undetermined. Children: Safety and efficacy not established. Hypersensitivity: Anaphylactic reactions have been reported. Special risk patients: Spinal cord compression or renal impairment have been reported. Worsening signs and symptoms: Drug initially causes transient increase in testosterone, which may lead to worsening of signs and symptoms of prostate cancer (eg, bone pain) during first few weeks of treatment.

Disclaimer ::

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