The Brand Name LUSTINE Has Generic Salt :: Lomustine 

LUSTINE  Is From Company Samarth Priced :: Rs. 384

LUSTINE have Lomustine is comes under Sub class Anti Neoplastic Agents of  Main Class Anti Neoplastic Agents

Main Medicine Class:: Anti Neoplastic Agents  Sub Medicine Class :: Anti Neoplastic Agents 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Lomustine  CAP  Rs. 384  4
Brand Name Company / Manufacturers Strength Unit Price / 4
 LUSTINE  Samarth  40MG  4 Rs. 384

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Samarth :: LUSTINE  Lomustine  Anti Neoplastic Agents Anti Neoplastic Agents

Indications for Drugs ::

Brain tumours; Hodgkin’s disease; Lung cancer; Malignant melanoma

Drug Dose ::

Oral Brain tumours, Hodgkin’s disease, resistant or relapsed, Malignant melanoma, Lung cancer Adult: 100-130 mg/m2 as a single dose every 6 wk. Adjust dose according to platelet and leukocyte counts. Compromised marrow function: 100 mg/m2 as a single dose every 6 wk. Child: 75-150 mg/m2 as a single dose every 6 wk. Readjust dose according to platelet and leukocyte counts. Renal impairment: CrCl (ml/min) 10-50 Admin 75% of normal dose. <10 Admin 25-50% of normal dose. Contraindication ::

Pregnancy and lactation.

Drug Precautions ::

Monitor CBC with differential platelet count wkly for at least 6 wk after a dose. Periodically perform pulmonary function studies and LFTs.

Drug Side Effects ::

Pulmonary infiltrates, pulmonary fibrosis, nausea, vomiting, hepatotoxicity, nephrotoxicity, stomatitis, alopecia, disorientation, lethargy, dysarthria, ataxia, visual disturbances. Potentially Fatal: Delayed bone marrow suppression and permanent marrow damage following prolonged use.

Pregnancy category ::
Pregnancy category

4

Drug Mode of Action ::  

Lomustine inhibits the synthesis of DNA and RNA via alkylation although carbamoylation and modification of cellular proteins may also be involved.

Drug Interactions ::

Increased levels/effects with CYP2D6 inhibitors.

 

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.