PRESENTATIONS OF HYPOPITUITARISM This depends on the hormones which are deficient. GH deficiency causes growth disorder and abnormal body structure. Gonadotrophin deficiency causes infertility, menstrual and sexual dysfunction and loss of secondary sexual characteristics in men. TSH and ACTH deficiency cause growth retardation, hypothyroidism, adrenal insufficiency. Mineralocorticoid action is retained....
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HYPOTHALAMIC, PITUITARY AND OTHER SELLAR MASSES Pituitary tumors , Pituitary adenomas : Commonest tumors are pituitary adenomas. These are benign and their features depend on the cell type from which they occur. They may arise from PRL, GH, ACTH, TSH, LH and FSH producing cells r;esulting in features of hypersecretion of...
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Chronic pancreatitis Diseases Symptoms Diagnosis and Treatment Chronic pancreatitis Pregentation · Abdominal pain · Steatorrhea. A form of pancreatitis that results from repeated or massive pancreatic injury, marked by the formation of scar tissue, which leads to malfunction of the pancreas Irreversible: Progressive destruction of the pancreas Results in both...
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Systemic Lupus Erythematosus (SLE) Diagnosis Symptoms and Treatment Systemic Lupus Erythematosus (SLE) Systemic Lupus Erythematosus (SLE) is an autoimmune disease of unknown etiology in which there is tissue damage by pathogenic antibodies. Multisystem autoimmune inflammatory disease characterized by fluctuating, chronic course; varies from mild to severe and may be life-threatening...
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Rheumatoid Arthritis Causes Symptoms Diagnosis and Treatment Rheumatoid Arthritis Rheumatoid arthritis is a chronic multisystem disease. There are systemic manifestations. There is persistent inflammatory synovitis. chronic systemic disease marked by inflammation of multiple synovial joints,Involves peripheral joints symmetrically. There is damage of cartilage and bone. Patients typically complain of joint...
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Systemic Sclerosis (Scleroderma) Systemic Sclerosis Classification Epidemiology Pathology Prognosis and Complications It is a chronic multisystem disorder. There is thickening of the skin due to accumulation of connective tissue affecting the structure and function of gastrointestinal system (GIT), lungs, heart, kidneys and other organs. There is vascular damage, and other...
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Diagnosis Systemic Sclerosis — Scleroderma (systemic sclerosis [SSc]) is a chronic disease of unknown cause characterized by diffuse fibrosis of skin and visceral organs and vascular abnormalities History Raynaud phenomenon is frequently the initial complaint. Skin thickening, “puffy hands,” and gastroesophageal reflux disease (GERD) are often noted early in the...
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Vasculitis Syndrome Vasculitis is a disease of blood vessels with inflammation and damage. Vasculitis may be a disease of the blood vessels itself or it may be secondarily affected due to a systemic disease. destruction of blood vessel walls, with subsequent aneurysm formation, bleeding, thrombosis, or ischemia in the various...
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Sarcoidosis It is a chronic, multisystem disorder of unknown cause. chronic multisystem disease of unknown etiology, characterized by noncaseating (hard) granulomas and lymphocytic alveol, Sarcoidosis is a noninfectious, multisystem granulomatous disease of unknown cause, commonly affecting young and middle-aged adults. Almost any other organ may be involved, including liver, spleen,...
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Disease of Joints and Musculoskeletal Disorders OSTEOARIRITIS Also called degenerative joint disease. Hip osteoarthritis is more common in men and small joints and knee OA is more common in women. There is damage to cartilage, remodeling and hypertrophy of bone. There is bone and muscle wasting. OSTEOARIRITIS Clinical Features ·...
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