Mycoplasma and Chalmydial Infections MYCOPLASMA INFECTIONS

Mycoplasma and Chalmydial Infections MYCOPLASMA INFECTIONS

MYCOPLASMA INFECTIONS

• Mycoplasma are smallest free-living organisms. They cause upper and lower respiratory tract disease. “!”he organism is M. pneumoniae.

Mycoplasma and Chalmydial Infections MYCOPLASMA INFECTIONS

Age affected is

• 5-20 years.

Mycoplasma and Chalmydial Infections pulmonary manifestations

Signs and Symptoms

• There is headache,
• cough,
• tracheobronchitis,
• pneu­monia.
• There may be myalgias.
• Auscultation of lungs may be normal.
• X-ray shows pneumonia.

CHLAMYDIAL INFECTIONS Extra-pulmonary manifestations

Extra-pulmonary manifestations

• may be Steven­Johnson syndrome,
• myocarditis and pericarditis.

Mycoplasma and Chalmydial Infections Treatment

• May not be required as it is self-limited.
• Doxycycline,
• Clarithromycin,
• Azithromycin,
• Levofloxacin are all effective for community ac­quired pneumonias.
• For hospitalized patients,
• IV Ceftriaxone or
• Levofloxacin may be used.

CHLAMYDIAL INFECTIONS

CHLAMYDIAL INFECTIONS

• C. pneumoniae is a common cause of upper respi­ratory tract infection in children and young adults.
• It may also have a role in atherosclerotic heart dis­ease, asthma, sarcoidosis.
• It can also cause endocarditis, peritonitis, pleuritis and Reiter’s syndrome i.e. Conjunctivitis, Urethritis, Arthritis, and Mucocutaneous lesions.
• C. trachomatis causes trachoma, and sexually trans­mitted diseases which may also affect newborn in­fants.
• C. psittaci causes an infectious disease of birds and mammals called ornithosis. There is fever, headache, cough, pneumonia, myalgia, epistaxis, GI symptoms.
• C. i>s for Chlamydia.

CHLAMYDIAL INFECTIONS Treatment

• Chlamydia responds to tetracycline and eryth­romycin 2 gm per day for 2 weeks.