Details About Generic Salt ::  Azelast1

Main Medicine Class::    

(ah-ZELL-ass-teen HIGH-dore-KLOR-ide)
Nasal spray
137 mcg/spray
Class: Antihistamine


Drugs Class ::

 Action Competitively antagonizes histamine at H1 receptor sites.

Indications for Drugs ::

 Indications Treatment of symptoms of seasonal allergic rhinitis, such as rhinorrhea, sneezing, and nasal pruritus; treatment of symptoms of vasomotor rhinitis, such as rhinorrhea, nasal congestion, and postnasal drip.

Drug Dose ::


Seasonal Allergic Rhinitis Adults and children (12 yr and over) Nasal Inhalation 2 sprays per nostril bid. Children (5 to 11 yr) Nasal Inhalation 1 spray per nostril bid.

Vasomotor Rhinitis Adults and children (12 yr and over): Nasal Inhalation 2 sprays per nostril bid.

Contraindication ::

 Contraindications Standard considerations.

Drug Precautions ::


Pregnancy: Category C. Lactation: Undermined. Children: Safety and efficacy not established in seasonal allergic rhinitis in children under 5 yr. Elderly: Select dose with caution, reflecting greater frequency of decreased hepatic, renal, or cardiac function and comorbidity.


Drug Side Effects ::

 Adverse Reactions

CARDIOVASCULAR: Flushing; hypertension; tachycardia. CNS: Somnolence; headache; fatigue; dizziness; hyperkinesias; hypoesthesia; vertigo; anxiety; depersonalization; depression; nervousness; sleep disturbances; abnormal thinking. DERMATOLOGIC: Contact dermatitis; eczema; hair and follicle infection; furunculosis. EENT: Nasal burning; pharyngitis; paroxysmal sneezing; rhinitis; epistaxis; conjunctivitis; glossitis; burning throat; laryngitis; eye abnormality; eye pain; watery eyes; sinusitis. GI: Bitter taste; dry mouth; nausea; constipation; gastroenteritis; ulcerative stomatitis; vomiting; aphthous stomatitis; loss of taste. GU: Albuminuria; amenorrhea; breast pain; hematuria; increased urinary frequency. HEPATIC: Increased ALT. METABOLIC: Weight increase; increased appetite. RESPIRATORY: Cough; asthma; bronchospasm. OTHER: Myalgia; cold symptoms; temporomandibular dislocation; allergic reaction; back pain; herpes simplex; viral infection; malaise; pain in extremities (eg, abdominal pain); dysesthesia.

Drug Mode of Action ::  

 Action Competitively antagonizes histamine at H1 receptor sites.

Drug Interactions ::


Alcohol, other CNS depressants: Effects may be enhanced by azelastine.

Drug Assesment ::


  • Obtain patient history, including drug history and any known allergies.
  • Assess for allergy symptoms (eg, rhinitis, nasal congestion, sneezing, nasal itching) before and periodically throughout therapy.
  • Monitor patient for dizziness and excessive drowsiness. If noted hold therapy and notify health care provider.
  • Monitor patient for CNS, GI, and general body side effects. Inform health care provider if noted and significant.

Drug Storage/Management ::


  • For intranasal administration only. Avoid spraying into the eyes.
  • Prime spray pump with 4 sprays before first use and with 2 sprays if unit has not been used for 3 or more days.
  • Have patient administer prescribed number of sprays twice daily.
  • Have patient instill into nostril with head upright. Have patient sniff for a few minutes after instillation.
  • Do not allow tip of container to touch nasal passage.
  • Do not use container on more than 1 patient.
  • Store spray bottle at controlled room temperature (36° to 77°F). Keep in upright position. Keep tightly closed and protect from freezing.

Drug Notes ::

 Patient/Family Education

  • Advise patient to read patient instruction sheet which accompanies each spray bottle of azelastin.
  • Explain name, dose, action, and potential side effects of drug.
  • Instruct patient to prime spray unit as directed in patient instruction sheet before first use and after storage for 3 or more days.
  • Ensure that patient understands how to properly administer spray.
  • Advise patient that if allergy symptoms are not controlled not to increase the dose of medication or frequency of use but to inform their health care provider. Inform patient that larger or more frequent dosing does not increase effectiveness and may cause drowsiness or other unwanted effects.
  • Advise patient that medication may cause drowsiness or dizziness and to not drive or perform other activities requiring mental alertness until tolerance is determined.
  • Caution patient that alcohol and other CNS depressants (eg, sedatives) will have additional sedative effects if taken with azelastine.
  • Caution patient not to take any OTC antihistamines while taking this medication unless advised by their health care provider.
  • Advise patient to take sips of water, suck on ice chips or sugarless hard candy, or chew sugarless gum if dry mouth occurs.
  • Advise patient that bitter taste is a frequent side effect and to notify their health care provider it this occurs and is bothersome.
  • Advise women to notify health care provider if pregnant, plan on becoming pregnant, or breastfeeding.
  • Instruct patient to stop taking drug and immediately report any of these symptoms to health care provider: dizziness, excessive drowsiness.
  • Caution patient to not take any prescription or OTC medications, or dietary supplements, unless advised to do so by health care provider.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.


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