Dorzolam

Details About Generic Salt ::  Dorzolam

Main Medicine Class:: Carbonic anhydrase inhibitor   

(dore-ZOLE-uh-mide)
Trusopt
Class: Carbonic anhydrase inhibitor

 

Drugs Class ::

 Action Inhibits carbonic anhydrase enzyme, reducing rate of aqueous humor formation and thus lowering intraocular pressure (IOP).

Indications for Drugs ::

 Indications Treatment of elevated IOP in patients with ocular hypertension or open-angle glaucoma.

Drug Dose ::

 Route/Dosage

ADULTS: Ophthalmic One drop in affected eye(s) tid.

Contraindication ::

 Contraindications Hypersensitivity to other sulfonamides.

Drug Precautions ::

 Precautions

Pregnancy: Category C. Lactation: Unknown. Children: Safety and efficacy not established. Renal impairment: Not recommended for use in patients with severe renal impairment. Hepatic impairment: Use with caution. Contact lenses: Do not administer while wearing soft contact lenses; preservative may be absorbed by soft contact lenses. Concomitant use of oral carbonic anhydrase inhibitors: Not recommended. Bacterial keratitis: Can occur by using contaminated eye drops.

PATIENT CARE CONSIDERATIONS


Drug Side Effects ::

 Adverse Reactions

CNS: Headache. EENT: Ocular burning, stinging or discomfort; superficial punctate keratitis; blurred vision; tearing; conjunctivitis; ocular dryness; photophobia; ocular allergic reaction. OTHER: Nausea; bitter taste.

Drug Mode of Action ::  

 Action Inhibits carbonic anhydrase enzyme, reducing rate of aqueous humor formation and thus lowering intraocular pressure (IOP).

Drug Interactions ::

 Interactions

None well documented.

Drug Assesment ::

 Assessment/Interventions

  • Obtain patient history.
  • Obtain baseline lab work including electrolytes and RBCs.
  • Note baseline intraocular pressure before starting medication.
OVERDOSAGE: SIGNS & SYMPTOMS
  Electrolyte imbalance, acidotic state, possible CNS effects

Drug Storage/Management ::

 Administration/Storage

  • Wash hands before and after using.
  • To avoid contamination, do not touch tip of container to any surface or to eye structures.
  • Administer only to affected eye.
  • Gently apply pressure over nasolacrimal drainage system for 1 to 2 min after administration.
  • Replace cap after administration and keep tightly closed when not in use.
  • If used concomitantly with other topical ophthalmic drug products, wait 10 min between administering medications.
  • Do not use with soft contact lenses. They may absorb the preservative.
  • Other therapeutic interventions should be used in conjunction with dorzolamide in the treatment of acute narrow angle glaucoma.
  • Store at room temperature, protected from light.

Drug Notes ::

 Patient/Family Education

  • Instruct patient in proper administration of eye drop medications.
  • Instruct patient about the need to keep the tip of the dropper clean to prevent eye infections.
  • Inform patient that eye drops commonly produce transient stinging or discomfort upon administration, and to notify healthcare provider if they are severe.
  • Stress need to return to healthcare provider frequently for monitoring of eye pressure.
  • Inform patient not to wear soft contact lenses while using this medication.
  • Inform patient that they may experience a bitter taste in mouth immediately after administration.
  • Explain the need to be cautions when driving or participating in activities requiring close hand-eye coordination.
  • Instruct patient to notify the healthcare provider if any symptoms of eye infection (ie, burning, redness, itching, possible discharge) occur.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.

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