Article Contents ::
- 1 Details About Generic Salt :: Doxycycl
- 2 Main Medicine Class:: Antibiotic,Tetracycline
- 3 (DOX-ee-SIGH-kleen) Bio-Tab, Doryx, Doxy 100, Doxy 200, Doxy Caps, Doxychel Hyclate, Monodox, Periostat, Vibramycin, Vibramycin IV, Vibra-Tabs, Alti-Doxycycline, Apo-Doxy, Apo-Doxy Tabs, Doryx, Doxy-Tec, Doxycin, Novo-Doxylin, Nu-Doxycycline, Rho-Doxycycline, Vibra-Tabs C-Pak Class: Antibiotic/Tetracycline
- 4 Drugs Class ::
- 5 Disclaimer ::
- 6 The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
Details About Generic Salt :: Doxycycl
Main Medicine Class:: Antibiotic,Tetracycline
Bio-Tab, Doryx, Doxy 100, Doxy 200, Doxy Caps, Doxychel Hyclate, Monodox, Periostat, Vibramycin, Vibramycin IV, Vibra-Tabs, Alti-Doxycycline, Apo-Doxy, Apo-Doxy Tabs, Doryx, Doxy-Tec, Doxycin, Novo-Doxylin, Nu-Doxycycline, Rho-Doxycycline, Vibra-Tabs C-Pak
Drugs Class ::
Action Inhibits bacterial protein synthesis.
Indications for Drugs ::
Indications Treatment of infections due to susceptible strains of gram-positive and gram-negative bacteria, Rickettsia, Mycoplasma pneumoniae; treatment of trachoma and susceptible infections when penicillins are contraindicated; treatment of acute intestinal amebiasis, uncomplicated gonorrhea in adults; prophylaxis of malaria due to Plasmodium falciparum Periodontitis: Adjunct treatment to scaling and root planing to promote attachment level gain and reduce pocket depth. Unlabeled use(s): Prevention of “traveler’s diarrhea.”
Drug Dose ::
ADULTS and children > 8 YR AND > 45 KG: PO/IV 200 mg day 1, then 100 to 200 mg qd in single or divided doses. CHILDREN > 8 YR AND < 45 KG: PO/IV 4.4 mg/kg day 1, then 2.2 mg/kg in single or 2 divided doses. CHILDREN > 8 YR: 2 mg/kg/day; do not exceed 100 mg/day.
Acute Gonococcal Infection
ADULTS & CHILDREN < 8 YR (AND ³ 45 KG): PO 200 mg immediately, then 100 mg at bedtime day 1, then 200 mg qd for 3 days. Single visit alternative: PO 300 mg immediately, followed by 300 mg in 1 hr.
ADULTS (NONPREGNANT PENICILLIN-ALLERGIC): PO/IV 100 mg bid for 2 wk.
ADULTS & CHILDREN ³ 8 YR: PO 100 mg bid for 7 days.
ADULTS: PO 100 mg qd, beginning 1 to 2 days before travel and continuing for 4 wk after leaving area.
ADULTS: PO 20 mg bid as an adjunct following scaling and root planing for £ 9 mo. Administer tablets ³ 1 hr before or 2 hr after meals; administer capsules ³ 1 hr before the morning and evening meals.
Contraindications Hypersensitivity to tetracyclines; nursing mothers, infancy, and childhood (Periostat).
Drug Precautions ::
Pregnancy: Category D. Lactation: Excreted in breast milk. Children: Not recommended in children < 8 yrs; abnormal bone formation and tooth discoloration may result. Anticoagulants: May need to decrease dosage of anticoagulant. Hepatic effects: Doses > 2 g/day have been associated with liver failure; monitor function and avoid other hepatotoxic drugs. Outdated product: Do not use; degradation products of drug are highly nephrotoxic. Photosensitivity: May occur; avoid exposure to sunlight or ultraviolet light. Prolonged use: May result in thrombophlebitis; use oral form whenever reasonable. Renal impairment: Dosage reduction is required. Superinfection: Prolonged use may result in bacterial or fungal overgrowth.
PATIENT CARE CONSIDERATIONS
Drug Side Effects ::
CNS: Pseudotumor cerebri, manifested by headache and blurred vision. DERM: Rash; photosensitivity. GI: Diarrhea; nausea; vomiting; abdominal pain or discomfort; anorexia; bulky, loose stools; sore throat; glossitis. HEMA: Hemolytic anemia; thrombocytopenia; neutropenia. OTHER: Hypersensitivity reactions (eg, urticaria, anaphylaxis, pericarditis).
Drug Mode of Action ::
Action Inhibits bacterial protein synthesis.
Drug Interactions ::
Antacids containing aluminum, zinc, calcium, magnesium, bismuth salts, divalent/trivalent cations: May decrease oral absorption of doxycycline. Barbiturates, carbamazepine, hydantoins: May increase metabolism of and decrease effect of doxycycline. Digoxin: May increase digoxin serum levels. Iron salts: May decrease absorption of doxycycline. Methoxyflurane: Increased potential for nephrotoxicity exists; do not use together. Penicillins: May interfere with bactericidal action of penicillins.
Drug Assesment ::
- Obtain patient history, including drug history and any known allergies.
- Review baseline WBC and BUN and monitor throughout therapy.
- Withhold drug and notify physician if GI disturbances develop.
- Monitor body temperature.
- Inform physician of signs/symptoms of superinfection.
Drug Storage/Management ::
- Do not administer oral form with antacids.
- Do not inject via IM or SC route.
- Reconstitute vial contents with 10 mL of Sterile Water for Injection. Dilute further with D5W or normal saline to make concentration of 0.1 to 1 mg/ml.
- For solutions diluted with Lactated Ringer’s Injection or 5% Dextrose in Lactated Ringer’s, use within 6 hr of reconstitution. Discard any remaining solution.
- For solutions diluted with other preparations, store up to 72 hr before infusion. Complete infusion within 12 hr to ensure stability. Keep solution refrigerated and protect from light.
Drug Notes ::
- Instruct patient not to take medication with antacids.
- Caution patient to avoid exposure to sunlight and to use sunscreen or wear protective clothing to avoid photosensitivity reaction.
- Explain rationale and techniques for oral hygiene.
- Tell patient to increase fluid intake and to take medication after meals.
- Inform patient of possible skin rash (eg, maculopapular, erythematous).
- Instruct patient to report any visual changes and any additional infections to physician.
- Explain missed medication procedure: < 2 hr, take medication; > 2 hr, wait until next scheduled dose. Do not double up on medication.