Details About Generic Salt ::  Esomepra

Main Medicine Class:: Gastrointestinal,Proton Pump Inhibitor   

Nexium

Class: Gastrointestinal/Proton Pump Inhibitor

 

Drugs Class ::

 Action Suppresses gastric acid secretion by blocking proton pump within gastric parietal cells.

Indications for Drugs ::

 Indications Treatment of heartburn and other symptoms of gastroesophageal reflux disease (GERD); short-term treatment in healing and symptomatic resolution of erosive esophagitis; maintain symptom resolution and healing of erosive esophagitis; in combination with amoxicillin and clarithromycin for treatment of organism Helicobacter pylori infection and duodenal ulcer disease to eradicate H. pylori.

Drug Dose ::

 Route/Dosage

Healing of Erosive Esophagitis

ADULTS: PO 20 or 40 mg once daily for 4 to 8 wk.

Maintenance of Healing of Erosive Esophagitis

ADULTS: PO 20 mg once daily.

Symptomatic GERD

ADULTS: PO 20 mg once daily for 4 wk.

H. pylori Eradication to Reduce Risk of Duodenal Ulcer Recurrence

ADULTS: PO 40 mg once daily for 10 days in combination with amoxicillin 1000 mg bid and clarithromycin 500 mg bid for 10 days.

Contraindication ::

 Contraindications Standard considerations.

Drug Precautions ::

 Precautions

Pregnancy: Category B. Lactation: Undetermined. Children: Safety and efficacy not determined.

PATIENT CARE CONSIDERATIONS

Drug Side Effects ::

 Adverse Reactions

CNS: Headache. EENT: Dry mouth. GI: Diarrhea; nausea; flatulence; abdominal pain; constipation.

Drug Mode of Action ::  

 Action Suppresses gastric acid secretion by blocking proton pump within gastric parietal cells.

Drug Interactions ::

 Interactions

Drugs dependent on gastric pH for bioavailability (ketoconazole, iron salts, digoxin): Absorption of these drugs may be affected.

Drug Assesment ::

 Assessment/Interventions

• Obtain patient history, including drug history and any known allergies. Note history of liver disease.
• Assess for bloody or coffee ground emesis and black tarry stools.
• Assess for symptoms of esophageal reflux (eg, heart burn, acid regurgitation) or peptic ulcer activity (eg, indigestion, abdominal pain, nausea).
• Assess for headache and dry mouth.
• Monitor elimination patterns, and document any problems such as constipation or diarrhea.

OVERDOSAGE: SIGNS & SYMPTOMS   Confusion, drowsiness, blurred vision, tachycardia, nausea, diaphoresis, flushing, headache, dry mouth

Drug Storage/Management ::

 Administration/Storage

• Do not crush or chew; swallow capsule whole. If patient has difficulty swallowing capsule whole, open the capsule and gently mix the pellets with 1 tablespoon of cool or cold applesauce in a small bowl. Swallow mixture immediately without chewing. Do not crush or chew the pellets. Discard remaining pellet/applesauce mixture.
• Administer once daily ³ 1 hr before meals.
• Store at controlled room temperature. Keep container tightly closed.

Drug Notes ::

 Patient/Family Education

• Explain name, dose, action, and potential side effects of drug.
• Instruct patient to not crush or chew medication and to swallow the capsule whole.
• Advise patient that if experiencing difficulty swallowing the capsule, to open the capsule and gently mix the pellets with 1 tablespoon of cool or cold applesause and then immediately swallow the mixture without chewing. Remind patient that pellets should not be crushed or chewed and that the pellet/applesauce mixture should not be stored for future use.
• Instruct patient to take each dose ³ 1 hr before meals.
• Inform patient that antacids may be taken concurrently with esomeprazole.
• Remind patient that esomeprazole should be taken daily and not “as needed” or only when symptoms are present.
• Instruct patient to notify physician if pregnant, planning on becoming pregnant, or breastfeeding.
• Advise patient to report any of the following symptoms to the physician: bloody or coffee ground emesis, black tarry stools, recurrent heart burn, recurrent indigestion or abdominal pain, increasing need for antacid use.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.