Details About Generic Salt ::  Oxycodon

Main Medicine Class:: Narcotic analgesic combination   

Tablets: 5 mg oxycodone HCl/325 mg acetaminophen, Tablets: 7.5 mg oxycodone HCl/500 mg acetaminophen, Tablets: 10 mg oxycodone HCl/650 mg acetaminophen, Roxicet, Tablets: 5 mg oxycodone HCl/325 mg acetaminophen, Solution, oral: 5 mg oxycodone HCl/325 mg acetaminophen, Roxicet 5/500, Caplets: 5 mg oxycodone/500 mg acetaminophen, Roxilox, Capsules: 5 mg oxycodone HCl/500 mg acetaminophen, Tylox, Capsules: 5 mg oxycodone HCl/500 mg acetaminophen, Endocet, Oxycocet, Percocet-Demi
Class: Narcotic analgesic combination


Drugs Class ::

 Action Acetaminophen inhibits synthesis of prostaglandins and peripherally blocks pain impulse generation, whereas, oxycodone binds to opiate receptors in CNS. Combination has synergistic effect on alleviating pain.

Indications for Drugs ::

 Indications Relief of moderate-to-moderately severe pain.

Drug Dose ::


ADULTS: PO 5 mg (1 tablet, caplet, or teaspoonful) q 6 hr prn.

Contraindication ::

 Contraindications Hypersensitivity to acetaminophen, oxycodone or similar compounds.

Drug Precautions ::


Pregnancy: Category C. Lactation: Undetermined. Children: Safety and efficacy not established. Special Risk Patients: Use with caution in elderly, debilitated patients and those with hepatic or kidney failure or conditions accompanied by hypoxia or hypercapnia; monitor carefully to avoid decrease in pulmonary ventilation. Also use cautiously in patients sensitive to CNS depressants, postoperatively and in patients with pulmonary disease. Acute Abdominal Conditions: Diagnosis may be obscured; use with caution. Dependence: Can produce drug dependence; has abuse potential. Head Injury: Respiratory depression and elevation of CSF pressure may be exacerbated. Hepatic Impairment: Chronic alcoholics should limit acetaminophen intake to < 2 g/day. Sulfite Sensitivity: Use with caution in patients known to be sensitive, as some products contain bisulfites.


Drug Side Effects ::

 Adverse Reactions

CARDIOVASCULAR: Hypotension; bradycardia; tachycardia. CNS: Lightheadedness; dizziness; weakness; fatigue; sedation; euphoria; dysphoria; nervousness; headache; confusion. DERMATOLOGIC: Pruritus; rash. GI: Nausea; vomiting; constipation; abdominal pain; anorexia; biliary spasm; dry mouth. GU: Urinary retention or hesitancy. RESPIRATORY: Dyspnea; respiratory depression. OTHER: Malaise; tolerance; psychological and physical dependence with chronic use.

Drug Mode of Action ::  

 Action Acetaminophen inhibits synthesis of prostaglandins and peripherally blocks pain impulse generation, whereas, oxycodone binds to opiate receptors in CNS. Combination has synergistic effect on alleviating pain.

Drug Interactions ::


Anesthetics: Additive CNS depression.

Carbamazepine, hydantoins, sulfinpyrazone: Increased risk of hepatotoxicity.

CNS depressants (eg, barbiturates, tricyclic antidepressants, phenothiazines, sedatives, hypnotics, alcohol, other narcotics): Additive CNS depression.

Drug Assesment ::


  • Obtain patient history, including drug history and any known allergies.
  • Assess type, location, and intensity of pain before administration and frequently during treatment.
  • Assess vital signs before administration and periodically during treatment.
  • Assess for signs of narcotic dependence.
  • Assess bowel function routinely. If constipation develops, provide additional fluids, high-fiber foods, or stool softeners.
  • If respiratory depression develops, notify health care provider immediately and prepare emergency equipment.
  • If sedation or confusion develops, take safety precautions (eg, keep side rails up, assist with ambulation).
  • Evaluate patient's continuing need for therapy since psychological and physical dependence and tolerance may develop.
  Miosis, respiratory depression, CNS depression (somnolence progressing to stupor or coma), hepatic damage, circulatory collapse, cardiopulmonary arrest, death

Drug Storage/Management ::


  • Administer with food or milk to minimize GI irritation.
  • Store at room temperature in tightly-closed container.

Drug Notes ::

 Patient/Family Education

  • Instruct patient to take medication before pain becomes severe for greatest effectiveness.
  • Teach patient methods to prevent constipation.
  • Instruct patient to make position changes slowly if lightheadedness or sedation occurs.
  • Advise patient to avoid intake of alcoholic beverages or products containing alcohol while using this medication.
  • Advise patient that drug may cause drowsiness, and to use caution while driving or performing other tasks requiring mental alertness.
  • Caution patient that physical dependency and withdrawal symptoms may occur following discontinuation of long-term therapy.
  • Instruct patient not to take any otc medications without consulting health care provider.


Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.


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