Entecavir

Details About Generic Salt ::  Entecavir 

Main Medicine Class:: Anti Infectives   Sub Medicine Class ::  Anti Retrovirals (Drugs for HIV)

13N. ANTI-RETROVIRALS (DRUGS FOR HIV) in 13. ANTI-INFECTIVES
ENTECAVIR
GUANOSINE NUCLEOSIDE ANALOGUE | ANTI-VIRAL
PK: A: Rapid D: Extensive M: Partially hepatic E: Urine

Indications & Dose: DECOMPENSATED LIVER DISEASE PO Adult 1mg OD | LAMIVUDINE-RESISTANT VIREMIA PO Adult 1mg OD | NUCLEOSIDE TREATMENT-NAIVE PO Adult 0.5mg OD

Precautions: Renal impairment, patients receiving drugs that reduces renal function, hepatomegaly/other risk factors for liver disease

ADR: Serious: exacerbation of hepatitis, severe hepatomegaly steatosis, lactic acidosis, peripheral edema, Others: headache, nausea, fatigue, dizziness, diarrhea, dyspepsia, insomnia, somnolence, vomiting, raised liver enzyme levels

DDI: Serious Ribavirin/Ganciclovir/Valganciclovir increases drug efficacy

Diet: On empty stomach

Monitor: HIV status, LFTs, renal function, HIV viral load, CD4 count

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