Propantheline

Details About Generic Salt ::  Propantheline 

Main Medicine Class:: #N/A   Sub Medicine Class ::  #N/A

10D. DRUGS ACTING ON BLADDER in 10. GENITO-URINARY SYSTEM
PROPANTHELINE
ANTI-CHOLINERGIC | ANTI-SPASMODIC
also comes under 7G. Anti-Spasmodics in 7. Gastrointestinal System,  
PK: A: Poor M: Small intestine E: Urine

Indications & Dose: ENURESIS/ URINARY INCONTINENCE PO Adult Initially 15mg TID 30-60min before meals & 30mg at HS, max 120mg/day | GI SPASM & ADJUNCT IN PEPTIC ULCER PO Adult Initially 15mg TID 30-60min before meals & 30mg HS, max 120mg/day Child 1 month-12yr: 300µg/kg, max 15mg TID/QID, >12yr: Same as adult dose Elderly 7.5mg TID | HYPERHIDROSIS PO Adult Initially 15mg TID 30-60min before meals & 30mg at HS, max 120mg/day

Contra: Hypersensitivity, narrow-angle glaucoma, adhesions between the iris & lens, tachycardia, obstructive GI disease, paralytic ileus, severe UC, toxic megacolon complicating UC, hepatic/renal disease, myasthenia gravis, asthma, thyrotoxicosis, prostatic enlargement

Precautions: Children, elderly, diarrhea/fever

ADR: Serious: arrhythmia, hypotension, tachycardia, coma, paralytic ileus, angle-closure glaucoma, anaphylaxis, blurred vision, cycloplegia, mydriasis, increased ocular tension, pulmonary edema, Others: ataxia, insomnia, disorientation, delirium, drowsiness, excitement, dizziness, fever, hallucinations, dryness of mouth with difficulty in swallowing and talking, reduced bronchial secretions, constipation

DDI: Serious Ritodrine leads to tachycardia, Phenylephrine results LVF & pulmonary edema

Diet: Before food

Monitor: HR, BP, pulse, mental status

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