Pseudoephedrine

Details About Generic Salt ::  Pseudoephedrine 

Main Medicine Class:: Respiratory System   Sub Medicine Class ::  Anti Histamines and Nasal Decongestants

6B. ANTI-HISTAMINES AND NASAL DECONGESTANTS in 6. RESPIRATORY SYSTEM
PSEUDOEPHEDRINE
ALPHA/ß-AGONIST | NASAL DECONGESTANT
PK: A: Rapid D: 2.5 L/Kg (child), 2.64-3.51 L/kg (adult) M: Hepatic (<1%) E: Urine

Indications & Dose: NASAL CONGESTION PO Adult 60mg q4-6h, max 240mg/day Child 2-5 yr: 15mg q4-6h, max 60mg/day, 6-11 yr: 30mg q4-6h, max 120mg/day, >12yr: 60mg q4-6h, max 240mg/day

Contra: Hypersensitivity, HTN, alcohol intolerance, CAD, MAOIs

Precautions: CVD, DM, prostatic hyperplasia, seizure, thyroid dysfunction, renal impairment, elderly, glaucoma, MI

ADR: Serious: Tachycardia, hallucinations, seizures, cardiovascular collapse, agranulocytosis, hemolytic anemia, thrombocytopenia, Others: anxiety, restlessness, insomnia, skin rashes, anorexia, dry mouth

DDI: Serious TCAs activity may enhances/diminishes, MAOIs causes fatal hypertensive crisis, Tramadol causes ischaemic colitis, Caffeine increases BP, β-blockers increases pressor effect

Diet: With/Without food

Monitor: vital signs,neurologic & cardiovascularstatus regularly

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