The Brand Name REZOL Has Generic Salt :: Albendazole
REZOL Is From Company Chemo D. Priced :: Rs. 33
REZOL have Albendazole is comes under Sub class Anthelmintics of Main Class Anti Infectives
Main Medicine Class:: Anti Infectives Sub Medicine Class :: Anthelmintics
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Indications for Drugs ::
Helminthiasis, Echinococcosis, Neurocysticercosis, Enterobiasis, Ascariasis, Hookworm infections, Strongyloidiasis, Giardiasis, Filariasis
Drug Dose ::
Adult: PO Echinococcosis >60 kg: 400 mg twice daily; <60 kg: 15 mg>60 kg: 400 mg twice daily; <60 kg: 15 mg>2 yr: 400 mg as a single dose; 1-2 yr: 200 mg as a single dose.
Pregnancy and lactation. Neonates. Hypersensitivity, liver impairment.
Drug Precautions ::
Monitor blood counts and liver function. Administer within 7 days of start of normal menstruation in women of childbearing age. Adequate nonhormonal contraceptive measures must be taken during and for 1 mth after therapy. Perform liver function tests and blood counts before and every 2 wk during high dose therapy of hydatid disease.
Drug Side Effects ::
GI discomfort, headache, nausea, dizziness, allergic reactions, pruritus, raised liver enzymes, alopecia and dry mouth. Potentially Fatal: Bone marrow depression.
Pregnancy category ::
Drug Mode of Action ::
Albendazole sulfoxide (active metabolite), causes selective degeneration of cytoplasmic microtubules in intestinal and tegmental cells of intestinal helminths and larvae; glycogen is depleted, glucose uptake and cholinesterase secretion are impaired and desecratory substances accumulate intracellulary. ATP production decreases, causing energy depletion, immobilisation and worm death.
Drug Interactions ::
Increased serum concentrations w/ dexamethasone, praziquantel and cimetidine. Decreased serum concentrations w/ aminoquinoline (antimalarials), carbamazepine, phenobarbital, and phenytoin.