Roxithromycin

Details About Generic Salt ::  Roxithromycin 

Main Medicine Class:: Anti Infectives   Sub Medicine Class ::  Macrolides

13E. MACROLIDES in 13. ANTI-INFECTIVES
ROXITHROMYCIN
MACROLIDE ANTIBIOTIC | ANTI-INFECTIVE
PK: M: Hepatic E: Feces

Indications & Dose: BACTERIAL INFECT PO Adult 300mg/day in single/divided doses Child 5-8mg/kg/day, max 150mg BIDCaused by susceptible organisms

Contra: Hypersensitivity

Precautions: hepatic impairment, history of arrhythmia, Predisposition to QT interval prolongation

ADR: Serious: superinfection, hypersensitivity, SJS, TEN, cholestasis, hepatic dysfunction, tinnitus, agranulocytosis, pancreatitis, QT interval prolongation, arrhythmia, seizures, aggravate muscle weakness, Others: vertigo, thrombophlebitis, abdominal discomfort & cramp, nausea, vomiting, diarrhea, confusion, hallucinations

DDI: Serious Midazolam effects modestly increased, Digoxin levels increases, Carbamazepine toxicity increases

Diet: Before food

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