Article Contents ::
- 1 Details About Generic Salt :: Iron
- 2 Main Medicine Class:: Iron product
- 3 (iron DEX-tran) DexFerrum, InFeD, Infufer Class: Iron product
- 4 Drugs Class ::
- 5 Disclaimer ::
- 6 The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
Details About Generic Salt :: Iron
Main Medicine Class:: Iron product
DexFerrum, InFeD, Infufer
Class: Iron product
Drugs Class ::
Action Replenishes Hgb and depleted iron stores.
Indications for Drugs ::
Indications Treatment of iron deficiency anemia when oral administration of iron is unsatisfactory or impossible. Unlabeled use(s): Use with epoetin to ensure hematological response to epoetin.
Drug Dose ::
Prior to the first IV or IM iron dextran injection, give a 0.5 ml test dose by the same route, respectively. Anaphylactic reactions occurring following iron dextran injection are usually evident within a few minutes; however, at least 1 hr should elapse before the remainder of the therapeutic dose is given.
Iron Deficiency Anemia
ADULTS & CHILDREN: IM/IV with dose based on formula to determine amount of iron required to restore hemoglobin to normal levels (max 2 ml/day undiluted iron dextran):
Iron Replacement for Blood Loss
ADULTS & CHILDREN: TEST DOSE: IM/IV with dose based on formula that 1 ml of normocytic, normochromic RBC cells contains 1 mg of elemental iron (maximum 2 ml/day undiluted iron dextran):
Mg iron — blood loss (ml) × Hct
Each day’s dose should not exceed 0.5 ml (25 mg iron) for infants < 10 lb or 1 ml (50 mg iron) for children < 20 lb, or 2 ml (100 mg iron) for other patients.
Contraindications Anemia not associated with iron deficiency.
Drug Precautions ::
Pregnancy: Safety not established. Based on animal studies, avoid if possible. Lactation: Undetermined. Children: Not recommended in children < 4 mo. Allergies/Asthma: Use drug with caution in patients with history of significant allergies/asthma. Arthritis: Patients with iron deficiency anemia and rheumatoid arthritis may have acute exacerbation of joint pain and swelling after IV administration. Hepatic impairment: Use drug with extreme caution in severe hepatic impairment. Hypersensitivity: Hypersensitivity, including anaphylaxis, may occur. Have epinephrine immediately available.
PATIENT CARE CONSIDERATIONS
Drug Side Effects ::
CV: Hypotension; peripheral vascular flushing (IV). CNS: Headache; dizziness; malaise; transitory paresthesias. DERM: Brown skin discoloration at IM injection site. GI: Nausea. HEMA: Leukocytosis. OTHER: Hypersensitivity (eg, fatal anaphylaxis, shortness of breath, urticaria, itching, arthralgia, myalgia, fever); pain and inflammation at injection site; sterile abscesses (IM); phlebitis at IV injection site; reactivation of arthritis in patients with inactive rheumatoid arthritis; backache; shivering. Delayed reactions may occur 1 to 2 days after administration.
Drug Mode of Action ::
Action Replenishes Hgb and depleted iron stores.
Drug Interactions ::
Chloramphenicol: May increase serum iron concentrations. INCOMPATIBILITIES: Do not mix with other medications or add to parenteral nutrition solutions for IV infusions.
Drug Assesment ::
- Obtain patient history, including drug history and any known allergies.
- Assess patient’s nutritional status and dietary history to determine possible causes of anemia.
- Monitor Hgb, Hct, and reticulocyte values; transferrin, ferritin, total ironbinding capacity; and plasma iron concentrations periodically during therapy.
- Assess patient for signs of anaphylaxis (eg, rash, pruritus, laryngeal edema, wheezing).
- Monitor BP and heart rate frequently during IV administration.
- Assess patient for symptoms of GI distress and constipation regularly throughout therapy.
- Provide diet high in iron (eg, organ meats; leafy, green vegetables; dried beans and peas; dried fruit; cereals).
- If constipation occurs, obtain order for laxative. Increase fiber and give additional fluids.
Drug Storage/Management ::
- Oral iron preparations should be discontinued before parenteral administration.
- Inject IM via Z-track technique into upper outer quadrant of buttock; never inject iron dextran into arm or other exposed areas. Use 2- to 3-inch 19- or 20-gauge needle.
- If patient is standing, weight should be placed on leg opposite injection site. If in bed, patient should be in lateral position with injection site uppermost.
- Change needles between withdrawal from container and injection to minimize staining of SC tissues. Stains usually are permanent.
- For IV administration, inject slowly at £ 1 ml/min.
- Store at room temperature.
Drug Notes ::
- Teach family and patient the name, dose, action, and side effects of iron.
- Advise patient to take additional fluids to prevent constipation.
- Teach patient that certain foods, such as coffee, tea, eggs, and milk, interact with iron.
- Teach patient and family the daily iron requirements (children 6 mo to 10 yr: 10 mg; adolescents 11 to 18 yr, male: 12 mg; adolescents 11 to 18 yr, female: 15 mg; adult women, pregnant: 30 mg; adult women, nonpregnant: 15 mg; adult men: 10 mg).