Details About Generic Salt ::  Milrinon

Main Medicine Class:: Cardiovascular   

(MILL-rih-nohn LAK-tate)
Primacor
Class: Cardiovascular

 

Drugs Class ::

 Action Has direct arterial vasodilator activity and positive inotropic effect; ncreases myocardial contractility.

Indications for Drugs ::

 Indications Short-term treatment of CHF.

Drug Dose ::

 Route/Dosage

ADULTS: IV Loading dose: 50 mcg/kg over 10 min; adjust infusion rate according to hemodynamic and clinical response.

Contraindication ::

 Contraindications Standard considerations.

Drug Precautions ::

 Precautions

Pregnancy: Category C. Lactation: Undetermined. Children: Safety and efficacy not established. Cardiovascular effects: Do not use in patients with severe obstructive aortic or pulmonic valvular disease; may exacerbate hypertrophic subaortic stenosis; may cause supraventricular and ventricular arrhythmias; may shorten atrioventricular node conduction. Renal impairment: Use drug with caution; monitor renal function. Dosage reduction, based on creatinine clearance, may be needed.

PATIENT CARE CONSIDERATIONS


Drug Side Effects ::

 Adverse Reactions

CV: Ventricular arrhythmia (eg, ventricular ectopic activity, nonsustained ventricular tachycardia, sustained ventricular tachycardia, ventricular fibrillation); supraventricular arrhythmia; hypotension; angina. CNS: Headaches; tremor. Thrombocytopenia. OTHER: Hypokalemia.

Drug Mode of Action ::  

 Action Has direct arterial vasodilator activity and positive inotropic effect; ncreases myocardial contractility.

Drug Interactions ::

 Interactions None well documented. INCOMPATIBILITIES: Precipitate forms if furosemide is injected into same IV line as milrinone; do not administer both in same IV line.

Drug Assesment ::

 Assessment/Interventions

  • Obtain patient history, including drug history and any known allergies.
  • Evaluate renal function and identify whether patient has severe obstructive aortic or pulmonic valvular disease.
  • Provide close cardiac and BP monitoring.
  • Be especially observant for supraventricular and ventricular arrhythmias and excessive decreases in BP and report to physician.
  • Carefully monitor fluid and electrolyte changes as well as renal function during therapy.
  • Observe IV site for signs of irritation. Rotate injection site every 48 hr.
  • Correct hypokalemia by potassium supplementation prior to and during use of drug.
  • Observe for other common side effects (headaches, hypokalemia, tremor and thrombocytopenia) and report to physician.
OVERDOSAGE: SIGNS & SYMPTOMS
  Hypotension

Drug Storage/Management ::

 Administration/Storage

  • For short-term (up to 5 days) IV use only.
  • Prepare drug for IV infusion by diluting with 0.45% or 0.9% Sodium Chloride Injection D5W.
  • Use infusion pump for administration.
  • Adjust maintenance infusion rate on the basis of hemodynamic and clinical response (maximum rate is 0.75 mcg/kg/min or 1.13 mg/kg/day).
  • Store at room temperature and protect from light.

Drug Notes ::

 Patient/Family Education

  • Explain what medication does.
  • Inform patient that treatment with this drug usually does not exceed 5 days.
  • Instruct patient to report these symptoms to physician: headache or tremors.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.

DOWNLOAD OUR ANDROID APP

One of the 1st in India.High Quality Generic Medicine Portal Android Application for Online Oreder & Information.

For More Join Our Membership and Get Additional 25% off on Meds, also get MLM Benefits to get a permanent earning source.

Join Membership How to Search Medicine
Android App

We would like to keep you updated with special notifications.