Details About Generic Salt ::  Triazola

Main Medicine Class:: Sedative and hypnotic,benzodiazepine   

(try-AZE-oh-lam)
Halcion,  Alti-Triazolam, APO-Triazo, Gen-Triazolam, Novo-Triolam
Class: Sedative and hypnotic/benzodiazepine

 

Drugs Class ::

 Action Potentiates action of GABA (gamma-aminobutyric acid), an inhibitory neurotransmitter, resulting in increased neuronal inhibition and CNS depression, especially in limbic system and reticular formation.

Indications for Drugs ::

 Indications Treatment of insomnia.

Drug Dose ::

 Route/Dosage

ADULTS: PO 0.125–0.5 mg at bedtime. ELDERLY OR DEBILITATED PATIENTS: Initiate with 0.125 mg until individual response is determined.

Contraindication ::

 Contraindications Hypersensitivity to benzodiazepines; pregnancy.

Drug Precautions ::

 Precautions

Pregnancy: Category X. Lactation: Undetermined. Children: Not for use in children < 18 yr. Special risk patients: Use drug with caution in elderly patients and patients with renal or hepatic impairment, depression or suicidal tendencies, drug abuse and dependence, chronic pulmonary insufficiency or apnea, seizure disorder. Dependence: Prolonged use (> 1–2 wk) can lead to dependence. Withdrawal syndrome may occur; taper dose gradually.

PATIENT CARE CONSIDERATIONS


Drug Side Effects ::

 Adverse Reactions

CNS: Anterograde amnesia; headache; nervousness; drowsiness; confusion; talkativeness; pprehension; irritability; euphoria; weakness; tremor; incoordination; memory impairment; depression; ataxia; dizziness; dreaming/nightmares; hallucinations; aradoxical reactions (eg, anger, hostility, mania, muscle spasms). DERM: Rash; photosensitivity. EENT: Visual or auditory disturbances; depressed hearing; taste disturbances. GI: Heartburn; nausea; vomiting; diarrhea; constipation; dry mouth; anorexia. HEMA: Blood dyscrasias including agranulocytosis; anemia; thrombocytopenia; eukopenia; neutropenia. HEPA: Hepatic dysfunction including hepatitis and jaundice. OTHER: Dependence/withdrawal syndrome (eg, confusion; abnormal perception of movement; depersonalization; muscle twitching; psychosis; paranoid delusions; eizures). Rebound sleep disorder (recurrence of insomnia worse than before treatment) may occur during first 3 nights after abrupt discontinuation.

Drug Mode of Action ::  

 Action Potentiates action of GABA (gamma-aminobutyric acid), an inhibitory neurotransmitter, resulting in increased neuronal inhibition and CNS depression, especially in limbic system and reticular formation.

Drug Interactions ::

 Interactions

Alcohol, CNS depressants (eg, narcotic sedatives): May cause additive CNS depressant effects. Cimetidine, disulfiram, omeprazole, oral contraceptives: Triazolam effects may increase. Digoxin: Serum digoxin concentrations may be increased. Theophylline: May antagonize sedative effects.

Drug Assesment ::

 Assessment/Interventions

  • Obtain patient history, including drug history and any known allergies. Identify potential for abuse and underlying depression.
  • Assess usual sleep patterns and define type of sleep alteration, ie, insomnia. Assess for modifiable causes of sleep disturbance, such as environmental noise, daytime sleeping and caffeine use.
  • Assess therapeutic response to therapy throughout usage.
  • Implement safety precautions to prevent injury (eg, assist with ambulation), particularly during initial treatment until individual response is determined.
  • Utilize general comfort measures to encourage sleep.
  • Implement environmental control measures when appropriate to enhance sleep.
  • Monitor for side effects, such as dizziness, drowsiness, headache, change in mood or mental status, GI disturbance, paradoxical excitation.
  • Monitor for daytime drowsiness or lethargy.
  • Assess for signs of dependence.

OVERDOSAGE: SIGNS & SYMPTOMS
  Somnolence, confusion, delirium, lack of coordination, ataxia, slurred speech, respiratory depression, coma, seizures

Drug Storage/Management ::

 Administration/Storage

  • Administer at bedtime with full glass of water.
  • Administer with food if GI upset occurs.
  • Administer lowest dosage until response is determined.
  • If patient exhibits possible suicidal tendencies, ensure that patient swallows drug and that patient does not have access to large quantities.
  • Store at room temperature in a tight, light-resistant container.

Drug Notes ::

 Patient/Family Education

  • Caution patient that this medication must not be taken during pregnancy or when pregnancy is possible. Advise patient to use reliable form of birth control while taking this drug.
  • Remind patient that medication should not be abruptly discontinued.
  • Review with patient and family other general sleep promotion measures, as well as what to avoid, such as caffeine and excessive exercise at bedtime.
  • Explain that medication may cause morning drowsiness or tiredness.
  • Caution patient regarding dependence potential.
  • Explain potential side effects and what to report to physician (onfusion, paradoxical excitement, headache, bleeding, recurrent sleep disorder).
  • Instruct patient to avoid intake of alcoholic beverages or other CNS depressants.
  • Advise patient to use caution while driving or performing other tasks requiring mental alertness.
  • Instruct patient not to take otc medications without consulting physician.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.

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