Details About Generic Salt ::  Bivaliru

Main Medicine Class:: Anticoagulant   

Angiomax

Class: Anticoagulant

 

Drugs Class ::

 Action Inhibits thrombin by reversibly binding to the catalytic site and the anion-binding exosite of circulating and clot-bound thrombin. Inhibits clot-bound and free, circulating thrombin, reducing the amount of active thrombin present for clot formation and extension.

Indications for Drugs ::

 Indications Anticoagulant in combination with aspirin in patients with unstable angina undergoing percutaneous transluminal coronary angioplasty (PTCA).

Drug Dose ::

 Route/Dosage

ADULTS: IV Bolus of 1 mg/kg followed by a 4-hr IV infusion at a rate of 2.5 mg/kg/hr. After the 4-hr infusion, an additional IV infusion of 0.2 mg/kg/hr for £ 20 hr may be given if needed. Bivalirudin is intended for concurrent use with aspirin (300 to 325 mg/day). Initiate treatment prior to PTCA.

Contraindication ::

 Contraindications Active major bleeding.

Drug Precautions ::

 Precautions

Pregnancy: Category B. Lactation: Undetermined. Children: Safety and efficacy not established.

Drug Side Effects ::

 Adverse Reactions

CV: Hypotension; hypertension; bradycardia. CNS: Headache; insomnia; anxiety; nervousness. GI: Nausea; vomiting; abdominal pain; dyspepsia. GU: Urinary retention. HEMA: Bleeding. OTHER: Back pain; pain; injection site pain; pelvic pain; fever.

Drug Mode of Action ::  

 Action Inhibits thrombin by reversibly binding to the catalytic site and the anion-binding exosite of circulating and clot-bound thrombin. Inhibits clot-bound and free, circulating thrombin, reducing the amount of active thrombin present for clot formation and extension.

Drug Interactions ::

 Interactions

Heparin, thrombolytics, warfarin: The risk of major bleeding may be increased. INCOMPATIBILITIES: Do not mix with other medications.

Drug Assesment ::

 Precautions

Pregnancy: Category B. Lactation: Undetermined. Children: Safety and efficacy not established.

Drug Storage/Management ::

 Precautions

Pregnancy: Category B. Lactation: Undetermined. Children: Safety and efficacy not established.

Drug Notes ::

 Precautions

Pregnancy: Category B. Lactation: Undetermined. Children: Safety and efficacy not established.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.