Details Descriptions About :: ankylosing spondylitis

Ankylosing spondylitis causes symptoms treatment 

Description of Ankylosing spondylitis

DescriptionAccording to dictionary definition  Ankylosing spondylitis (AS) is a form of arthritis that affects the spine. An affected individual experiences pain and stiffness from the neck radiating down to the lower back. Over the period, the vertebrae may grow or fuse with one another, which forms a rigid spine. The fusing of vertebrae and rigid spine may also result in a stooped-over posture.  Causes and Risk FactorsAccording to dictionary definition  There is no specific cause for the development of AS. However, some common causes involve genetic factors (individuals with a particular gene called HLA-B27 are at a greater risk of developing AS).

Common risk factors are:1. Age: Generally occurs in late adolescence or early adulthood2. Gender: Males are more prone to developing AS as compared to females3. Heredity: Presence of the HLA-B27 gene4. Family history of the disease5. Frequent gastrointestinal infections  Signs and SymptomsAccording to dictionary definition  Common symptoms include:1. Pain and stiffness in the lower back and hips, particularly worse in the mornings and after periods of inactivity2. Fever3. Fatigue4. Loss of appetite5. Eye inflammation (pain and redness) may also occur in some cases6. Lung and heart problems may also develop in some cases  InvestigationsAccording to dictionary definition  1. Your doctor may ask for the symptoms and examine you physically.2. You may be recommended to get some imaging tests done such as x-rays and magnetic resonance imaging (MRI).3. Measurements of the chest when breathing4. You may be asked to get some laboratory tests done such as blood tests to check for markers of inflammation.  TreatmentAccording to dictionary definition  There is no cure for AS. However, there are certain treatments that can lessen discomfort thereby improving function. The main purpose of treatment is to reduce pain and stiffness, prevent deformity, maintain a good posture, and preserve the ability to perform normal activities.1. Medications include:a) Nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin, ibuprofen, and naproxenb) Disease-modifying antirheumatic drugs (DMARDs) such as methotrexatec) Relatively new drugs called biologics such as certolizumab pegol (Cimzia), adalimumab (Humira), and etanercept(Enbrel)2. Exercise regularly: Daily moderate exercise regimen helps to lessen stiffness, strengthen the muscles around the joints, and prevent or reduce the risk of disability3. Surgery



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