Details About Generic Salt ::  Hydroxyz

Main Medicine Class::    

(high-DROX-ih-zeen HIGH-droe-KLOR-ide)
10 mg
25 mg
50 mg
100 mg
10 mg/5 mL
25 mg
50 mg
100 mg
Suspension, oral
25 mg/5 mL
50 mg/mL
Multipax, Novo-Hydroxyzide, Novo-Hydroxyzine, Nu-Hydroxyzine, PMS-Hydroxyzine
Class: Antipsychotic, Antihistamine


Drugs Class ::

 Action May be caused by suppression of activity in subcortical areas of CNS.

Indications for Drugs ::

 Indications Symptomatic relief of anxiety and tension associated with psychoneurosis; adjunct therapy in organic disease states with anxiety; management of pruritus caused by allergic conditions; sedative before and after general anesthesia (PO only).

IM route only: Relief of anxiety in acutely disturbed or hysterical patient; treatment of alcoholic delirium tremens or anxiety withdrawal symptoms; preoperative and postoperative and prepartum and postpartum adjunctive medication to permit reduction in narcotic dosage; alleviation of anxiety; control of emesis; adjunctive therapy in asthma.

Drug Dose ::


Anxiety Adults: PO/IM 50 to 100 mg qid.

Children over 6 yr: PO 50 to 100 mg/day in divided doses.

Children less than 6 yr: PO 50 mg/day in divided doses.

Pruritus Adults: PO/IM 25 mg tid to qid.

Children over 6 yr: PO 50 to 100 mg/day in divided doses.

Children less than 6 yr: PO 50 mg/day in divided doses.

Sedation Adults: PO 50 to 100 mg.

Children: PO 0.6 mg/kg.

Psychiatric and Emotional Emergencies (ie, including acute alcoholism) Adults: IM 50 to 100 mg stat and q 4 to 6 hr prn.

Nausea, Vomiting, and Analgesia (Adjunct) Adults: IM 25 to 100 mg.

Children: IM 1.1 mg/kg.

Preoperative and Postoperative Administration Adults: IM 25 to 100 mg.

Children: IM 1.1 mg/kg.

Prepartum and Postpartum Administration Adults: IM 25 to 100 mg.

Contraindication ::

 Contraindications Standard considerations.

Drug Precautions ::


Pregnancy: Safety not established; avoid use. Lactation: Undetermined.


Drug Side Effects ::

 Adverse Reactions

CARDIOVASCULAR: Chest tightness. CNS: Transitory drowsiness; involuntary motor activity, including tremor and convulsions. GI: Dry mouth. RESPIRATORY: Hypersensitivity reactions (eg, wheezing, shortness of breath).

Drug Mode of Action ::  

 Action May be caused by suppression of activity in subcortical areas of CNS.

Drug Interactions ::


Alcohol and CNS depressants: CNS depressant effects may be increased.

Drug Assesment ::


  • Obtain patient history, including drug history and any known allergies.
  • Monitor lying and standing BP and pulse periodically throughout course of therapy.
  • Assess degree of nausea and frequency and amount of emesis.
  • Assist with ambulation during initial course of therapy.
  • If CNS symptoms of dizziness or drowsiness occur, take safety precautions (eg, side rails up, bed low, assist with ambulation).
  • Notify health care provider if paradoxical CNS symptoms such as restlessness, insomnia, euphoria, tremors, or seizures occur.

Drug Storage/Management ::


  • Injectable form is for IM use.
  • Administer oral dose with meals to enhance absorption.
  • Shake suspension well before administration.

Drug Notes ::

 Patient/Family Education

  • Emphasize that drug is not to be used for every day stress and should not be used for more than 4 mo.
  • Advise patient that drug may cause drowsiness and other CNS reactions and to use caution while driving or performing other tasks requiring mental alertness.
  • Instruct patient to avoid intake of alcoholic beverages or any other CNS depressant drugs (eg, sleeping pills) while taking this drug.
  • Advise patient to avoid sudden position changes to prevent orthostatic hypotension.
  • Tell patient to avoid OTC medications unless approved by health care provider.
  • Instruct patient to report the following symptoms to health care provider: tremor, seizures, dizziness, wheezing, difficulty breathing, chest tightness, involuntary movements, dry mouth.
  • Instruct patient to take sips of water frequently, suck on ice chips or sugarless hard candy, or chew sugarless gum if dry mouth occurs.
  • Caution patient not to discontinue drug abruptly.

Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.


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