Home » Drug Salts » Pirbuter
Article Contents ::
- 1 Details About Generic Salt :: Pirbuter
- 2 Main Medicine Class:: Bronchodilator,Sympathomimetic
- 3
(pihr-BYOO-tuh-role ASS-uh-TATE)
Maxair Inhaler, Maxair Autohaler
Class: Bronchodilator/Sympathomimetic
Action Produces bronchodilation by relaxing bronchial smooth muscle through beta-2 receptor stimulation.
Indications Prevention and treatment of reversible bronchospasm associated with asthma or other obstructive pulmonary diseases.
Contraindications Hypersensitivity to drug components; cardiac arrhythmias associated with tachycardia.
Route/Dosage
ADULTS & CHILDREN ³ 12 YR: Inhalation 1 to 2 inhalations q 4 to 6 hr; not to exceed 12 inhalations/day.
Interactions
MAO inhibitors, tricyclic antidepressants: May increase the effects of pirbuterol.
Lab Test Interferences None well documented.
Adverse Reactions
CV: Palpitations; tachycardia; BP changes; chest tightness/pain/discomfort; angina; arrhythmias/skipped beats. CNS: Tremor; anxiety; confusion; fatigue; dizziness; nervousness; headache; weakness; hyperactivity/hyperkinesia/excitement; insomnia. EENT: Dry nose; throat irritation. GI: GI distress; dry mouth; diarrhea; nausea/vomiting. RESP: Cough; throat irritation. OTHER: Flushing; anorexia/appetite loss; unusual/bad taste; taste/smell change.
Precautions
Pregnancy: Category C. Children: Safety and efficacy in children £ 12 years of age have not been established. Lactation: Undetermined. Elderly: Lower doses may be required. Cardiovascular effects: Toxic symptoms in patients with cardiovascular disorders may occur. CNS effects: CNS stimulation may occur; use cautiously in patients with history of seizure or hyperthyroidism. Diabetes: Dosage adjustment of insulin or oral hypoglycemic agent may be required. Excessive use: Paradoxical bronchospasm and cardiac arrest have been associated with excessive inhalant use. Hypokalemia: Decreases in potassium levels have occurred. Labor and delivery: May inhibit uterine contractions and delay preterm labor. Tolerance: If previously effective dose fails to provide relief therapy may need to be reassessed.
PATIENT CARE CONSIDERATIONS
Administration/Storage
Give pressurized inhalation during second half of breath intake.
If > 1 inhalation is needed, wait 1 to 2 minutes before administering second dose.
Discard any discolored solutions of drug.
Store at room temperature in light-resistant container.
Assessment/Interventions
Obtain patient history, including drug history and any known allergies.
Obtain baseline ABGs prior to initiation of therapy.
Assess BP and pulse before and after each dose.
Assess for CNS response, and adjust dose and frequency accordingly.
To prevent respiratory depression, administer oxygen based on ABGs and symptoms.
Assess vital capacity and forced expiratory volume.
If 3 to 5 aerosol treatments have been given within 6 to 12 hours with minimal relief, notify physician and do not give further treatment.
OVERDOSAGE: SIGNS & SYMPTOMS
Tremor, palpitations, tachycardia, elevated blood pressure, anginal pain, hypokalemia, seizures
Patient/Family Education
Advise patient to take drug early in day to prevent insomnia.
Explain that implementing therapy in morning and after meals may reduce fatigue and improve lung ventilation.
Encourage patient to increase fluid intake to help liquify secretions.
Tell patient to report the following symptoms to physician: Dizziness, chest pain, palpitations, muscle spasms, headache, difficult urination, dyspnea or nervous tremor.
Explain that if no relief is obtained from normal daily dose, call physician instead of increasing dose. Also if > 3 aerosol treatments are needed in 24 hours, notify physician.
Tell patient to wait at least 1 to 2 min before administering second inhalation.
Instruct patient that regular, consistent use of medication is required for maximum benefits.
Explain benefits of and demonstrate technique for postural drainage and chest vibration.
Instruct patient not to take any otc medications without consulting physician.
Emphasize that it is important to avoid getting aerosol medication in eyes.
Tell patient to avoid smoking, smoke-filled rooms, and persons with respiratory infections.
Explain how to use and care for inhalers and any other respiratory equipment.
- 4 Drugs Class ::
- 5 Disclaimer ::
- 6 The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.
Details About Generic Salt :: Pirbuter
(pihr-BYOO-tuh-role ASS-uh-TATE) |
Maxair Inhaler, Maxair Autohaler |
Class: Bronchodilator/Sympathomimetic |
Action Produces bronchodilation by relaxing bronchial smooth muscle through beta-2 receptor stimulation.
Indications Prevention and treatment of reversible bronchospasm associated with asthma or other obstructive pulmonary diseases.
Contraindications Hypersensitivity to drug components; cardiac arrhythmias associated with tachycardia.
Route/Dosage
ADULTS & CHILDREN ³ 12 YR: Inhalation 1 to 2 inhalations q 4 to 6 hr; not to exceed 12 inhalations/day.
Interactions
MAO inhibitors, tricyclic antidepressants: May increase the effects of pirbuterol.
Lab Test Interferences None well documented.
Adverse Reactions
CV: Palpitations; tachycardia; BP changes; chest tightness/pain/discomfort; angina; arrhythmias/skipped beats. CNS: Tremor; anxiety; confusion; fatigue; dizziness; nervousness; headache; weakness; hyperactivity/hyperkinesia/excitement; insomnia. EENT: Dry nose; throat irritation. GI: GI distress; dry mouth; diarrhea; nausea/vomiting. RESP: Cough; throat irritation. OTHER: Flushing; anorexia/appetite loss; unusual/bad taste; taste/smell change.
Precautions
Pregnancy: Category C. Children: Safety and efficacy in children £ 12 years of age have not been established. Lactation: Undetermined. Elderly: Lower doses may be required. Cardiovascular effects: Toxic symptoms in patients with cardiovascular disorders may occur. CNS effects: CNS stimulation may occur; use cautiously in patients with history of seizure or hyperthyroidism. Diabetes: Dosage adjustment of insulin or oral hypoglycemic agent may be required. Excessive use: Paradoxical bronchospasm and cardiac arrest have been associated with excessive inhalant use. Hypokalemia: Decreases in potassium levels have occurred. Labor and delivery: May inhibit uterine contractions and delay preterm labor. Tolerance: If previously effective dose fails to provide relief therapy may need to be reassessed.
PATIENT CARE CONSIDERATIONS |
|
Administration/Storage
- Give pressurized inhalation during second half of breath intake.
- If > 1 inhalation is needed, wait 1 to 2 minutes before administering second dose.
- Discard any discolored solutions of drug.
- Store at room temperature in light-resistant container.
Assessment/Interventions
- Obtain patient history, including drug history and any known allergies.
- Obtain baseline ABGs prior to initiation of therapy.
- Assess BP and pulse before and after each dose.
- Assess for CNS response, and adjust dose and frequency accordingly.
- To prevent respiratory depression, administer oxygen based on ABGs and symptoms.
- Assess vital capacity and forced expiratory volume.
- If 3 to 5 aerosol treatments have been given within 6 to 12 hours with minimal relief, notify physician and do not give further treatment.
OVERDOSAGE: SIGNS & SYMPTOMS |
|
Tremor, palpitations, tachycardia, elevated blood pressure, anginal pain, hypokalemia, seizures |
|
Patient/Family Education
- Advise patient to take drug early in day to prevent insomnia.
- Explain that implementing therapy in morning and after meals may reduce fatigue and improve lung ventilation.
- Encourage patient to increase fluid intake to help liquify secretions.
- Tell patient to report the following symptoms to physician: Dizziness, chest pain, palpitations, muscle spasms, headache, difficult urination, dyspnea or nervous tremor.
- Explain that if no relief is obtained from normal daily dose, call physician instead of increasing dose. Also if > 3 aerosol treatments are needed in 24 hours, notify physician.
- Tell patient to wait at least 1 to 2 min before administering second inhalation.
- Instruct patient that regular, consistent use of medication is required for maximum benefits.
- Explain benefits of and demonstrate technique for postural drainage and chest vibration.
- Instruct patient not to take any otc medications without consulting physician.
- Emphasize that it is important to avoid getting aerosol medication in eyes.
- Tell patient to avoid smoking, smoke-filled rooms, and persons with respiratory infections.
- Explain how to use and care for inhalers and any other respiratory equipment.
Drugs Class ::
(pihr-BYOO-tuh-role ASS-uh-TATE) |
Maxair Inhaler, Maxair Autohaler |
Class: Bronchodilator/Sympathomimetic |
Action Produces bronchodilation by relaxing bronchial smooth muscle through beta-2 receptor stimulation.
Indications Prevention and treatment of reversible bronchospasm associated with asthma or other obstructive pulmonary diseases.
Contraindications Hypersensitivity to drug components; cardiac arrhythmias associated with tachycardia.
Route/Dosage
ADULTS & CHILDREN ³ 12 YR: Inhalation 1 to 2 inhalations q 4 to 6 hr; not to exceed 12 inhalations/day.
Interactions
MAO inhibitors, tricyclic antidepressants: May increase the effects of pirbuterol.
Lab Test Interferences None well documented.
Adverse Reactions
CV: Palpitations; tachycardia; BP changes; chest tightness/pain/discomfort; angina; arrhythmias/skipped beats. CNS: Tremor; anxiety; confusion; fatigue; dizziness; nervousness; headache; weakness; hyperactivity/hyperkinesia/excitement; insomnia. EENT: Dry nose; throat irritation. GI: GI distress; dry mouth; diarrhea; nausea/vomiting. RESP: Cough; throat irritation. OTHER: Flushing; anorexia/appetite loss; unusual/bad taste; taste/smell change.
Precautions
Pregnancy: Category C. Children: Safety and efficacy in children £ 12 years of age have not been established. Lactation: Undetermined. Elderly: Lower doses may be required. Cardiovascular effects: Toxic symptoms in patients with cardiovascular disorders may occur. CNS effects: CNS stimulation may occur; use cautiously in patients with history of seizure or hyperthyroidism. Diabetes: Dosage adjustment of insulin or oral hypoglycemic agent may be required. Excessive use: Paradoxical bronchospasm and cardiac arrest have been associated with excessive inhalant use. Hypokalemia: Decreases in potassium levels have occurred. Labor and delivery: May inhibit uterine contractions and delay preterm labor. Tolerance: If previously effective dose fails to provide relief therapy may need to be reassessed.
PATIENT CARE CONSIDERATIONS |
|
Administration/Storage
- Give pressurized inhalation during second half of breath intake.
- If > 1 inhalation is needed, wait 1 to 2 minutes before administering second dose.
- Discard any discolored solutions of drug.
- Store at room temperature in light-resistant container.
Assessment/Interventions
- Obtain patient history, including drug history and any known allergies.
- Obtain baseline ABGs prior to initiation of therapy.
- Assess BP and pulse before and after each dose.
- Assess for CNS response, and adjust dose and frequency accordingly.
- To prevent respiratory depression, administer oxygen based on ABGs and symptoms.
- Assess vital capacity and forced expiratory volume.
- If 3 to 5 aerosol treatments have been given within 6 to 12 hours with minimal relief, notify physician and do not give further treatment.
OVERDOSAGE: SIGNS & SYMPTOMS |
|
Tremor, palpitations, tachycardia, elevated blood pressure, anginal pain, hypokalemia, seizures |
|
Patient/Family Education
- Advise patient to take drug early in day to prevent insomnia.
- Explain that implementing therapy in morning and after meals may reduce fatigue and improve lung ventilation.
- Encourage patient to increase fluid intake to help liquify secretions.
- Tell patient to report the following symptoms to physician: Dizziness, chest pain, palpitations, muscle spasms, headache, difficult urination, dyspnea or nervous tremor.
- Explain that if no relief is obtained from normal daily dose, call physician instead of increasing dose. Also if > 3 aerosol treatments are needed in 24 hours, notify physician.
- Tell patient to wait at least 1 to 2 min before administering second inhalation.
- Instruct patient that regular, consistent use of medication is required for maximum benefits.
- Explain benefits of and demonstrate technique for postural drainage and chest vibration.
- Instruct patient not to take any otc medications without consulting physician.
- Emphasize that it is important to avoid getting aerosol medication in eyes.
- Tell patient to avoid smoking, smoke-filled rooms, and persons with respiratory infections.
- Explain how to use and care for inhalers and any other respiratory equipment.
Indications for Drugs ::
(pihr-BYOO-tuh-role ASS-uh-TATE) |
Maxair Inhaler, Maxair Autohaler |
Class: Bronchodilator/Sympathomimetic |
Action Produces bronchodilation by relaxing bronchial smooth muscle through beta-2 receptor stimulation.
Indications Prevention and treatment of reversible bronchospasm associated with asthma or other obstructive pulmonary diseases.
Contraindications Hypersensitivity to drug components; cardiac arrhythmias associated with tachycardia.
Route/Dosage
ADULTS & CHILDREN ³ 12 YR: Inhalation 1 to 2 inhalations q 4 to 6 hr; not to exceed 12 inhalations/day.
Interactions
MAO inhibitors, tricyclic antidepressants: May increase the effects of pirbuterol.
Lab Test Interferences None well documented.
Adverse Reactions
CV: Palpitations; tachycardia; BP changes; chest tightness/pain/discomfort; angina; arrhythmias/skipped beats. CNS: Tremor; anxiety; confusion; fatigue; dizziness; nervousness; headache; weakness; hyperactivity/hyperkinesia/excitement; insomnia. EENT: Dry nose; throat irritation. GI: GI distress; dry mouth; diarrhea; nausea/vomiting. RESP: Cough; throat irritation. OTHER: Flushing; anorexia/appetite loss; unusual/bad taste; taste/smell change.
Precautions
Pregnancy: Category C. Children: Safety and efficacy in children £ 12 years of age have not been established. Lactation: Undetermined. Elderly: Lower doses may be required. Cardiovascular effects: Toxic symptoms in patients with cardiovascular disorders may occur. CNS effects: CNS stimulation may occur; use cautiously in patients with history of seizure or hyperthyroidism. Diabetes: Dosage adjustment of insulin or oral hypoglycemic agent may be required. Excessive use: Paradoxical bronchospasm and cardiac arrest have been associated with excessive inhalant use. Hypokalemia: Decreases in potassium levels have occurred. Labor and delivery: May inhibit uterine contractions and delay preterm labor. Tolerance: If previously effective dose fails to provide relief therapy may need to be reassessed.
PATIENT CARE CONSIDERATIONS |
|
Administration/Storage
- Give pressurized inhalation during second half of breath intake.
- If > 1 inhalation is needed, wait 1 to 2 minutes before administering second dose.
- Discard any discolored solutions of drug.
- Store at room temperature in light-resistant container.
Assessment/Interventions
- Obtain patient history, including drug history and any known allergies.
- Obtain baseline ABGs prior to initiation of therapy.
- Assess BP and pulse before and after each dose.
- Assess for CNS response, and adjust dose and frequency accordingly.
- To prevent respiratory depression, administer oxygen based on ABGs and symptoms.
- Assess vital capacity and forced expiratory volume.
- If 3 to 5 aerosol treatments have been given within 6 to 12 hours with minimal relief, notify physician and do not give further treatment.
OVERDOSAGE: SIGNS & SYMPTOMS |
|
Tremor, palpitations, tachycardia, elevated blood pressure, anginal pain, hypokalemia, seizures |
|
Patient/Family Education
- Advise patient to take drug early in day to prevent insomnia.
- Explain that implementing therapy in morning and after meals may reduce fatigue and improve lung ventilation.
- Encourage patient to increase fluid intake to help liquify secretions.
- Tell patient to report the following symptoms to physician: Dizziness, chest pain, palpitations, muscle spasms, headache, difficult urination, dyspnea or nervous tremor.
- Explain that if no relief is obtained from normal daily dose, call physician instead of increasing dose. Also if > 3 aerosol treatments are needed in 24 hours, notify physician.
- Tell patient to wait at least 1 to 2 min before administering second inhalation.
- Instruct patient that regular, consistent use of medication is required for maximum benefits.
- Explain benefits of and demonstrate technique for postural drainage and chest vibration.
- Instruct patient not to take any otc medications without consulting physician.
- Emphasize that it is important to avoid getting aerosol medication in eyes.
- Tell patient to avoid smoking, smoke-filled rooms, and persons with respiratory infections.
- Explain how to use and care for inhalers and any other respiratory equipment.
Drug Dose ::
(pihr-BYOO-tuh-role ASS-uh-TATE) |
Maxair Inhaler, Maxair Autohaler |
Class: Bronchodilator/Sympathomimetic |
Action Produces bronchodilation by relaxing bronchial smooth muscle through beta-2 receptor stimulation.
Indications Prevention and treatment of reversible bronchospasm associated with asthma or other obstructive pulmonary diseases.
Contraindications Hypersensitivity to drug components; cardiac arrhythmias associated with tachycardia.
Route/Dosage
ADULTS & CHILDREN ³ 12 YR: Inhalation 1 to 2 inhalations q 4 to 6 hr; not to exceed 12 inhalations/day.
Interactions
MAO inhibitors, tricyclic antidepressants: May increase the effects of pirbuterol.
Lab Test Interferences None well documented.
Adverse Reactions
CV: Palpitations; tachycardia; BP changes; chest tightness/pain/discomfort; angina; arrhythmias/skipped beats. CNS: Tremor; anxiety; confusion; fatigue; dizziness; nervousness; headache; weakness; hyperactivity/hyperkinesia/excitement; insomnia. EENT: Dry nose; throat irritation. GI: GI distress; dry mouth; diarrhea; nausea/vomiting. RESP: Cough; throat irritation. OTHER: Flushing; anorexia/appetite loss; unusual/bad taste; taste/smell change.
Precautions
Pregnancy: Category C. Children: Safety and efficacy in children £ 12 years of age have not been established. Lactation: Undetermined. Elderly: Lower doses may be required. Cardiovascular effects: Toxic symptoms in patients with cardiovascular disorders may occur. CNS effects: CNS stimulation may occur; use cautiously in patients with history of seizure or hyperthyroidism. Diabetes: Dosage adjustment of insulin or oral hypoglycemic agent may be required. Excessive use: Paradoxical bronchospasm and cardiac arrest have been associated with excessive inhalant use. Hypokalemia: Decreases in potassium levels have occurred. Labor and delivery: May inhibit uterine contractions and delay preterm labor. Tolerance: If previously effective dose fails to provide relief therapy may need to be reassessed.
PATIENT CARE CONSIDERATIONS |
|
Administration/Storage
- Give pressurized inhalation during second half of breath intake.
- If > 1 inhalation is needed, wait 1 to 2 minutes before administering second dose.
- Discard any discolored solutions of drug.
- Store at room temperature in light-resistant container.
Assessment/Interventions
- Obtain patient history, including drug history and any known allergies.
- Obtain baseline ABGs prior to initiation of therapy.
- Assess BP and pulse before and after each dose.
- Assess for CNS response, and adjust dose and frequency accordingly.
- To prevent respiratory depression, administer oxygen based on ABGs and symptoms.
- Assess vital capacity and forced expiratory volume.
- If 3 to 5 aerosol treatments have been given within 6 to 12 hours with minimal relief, notify physician and do not give further treatment.
OVERDOSAGE: SIGNS & SYMPTOMS |
|
Tremor, palpitations, tachycardia, elevated blood pressure, anginal pain, hypokalemia, seizures |
|
Patient/Family Education
- Advise patient to take drug early in day to prevent insomnia.
- Explain that implementing therapy in morning and after meals may reduce fatigue and improve lung ventilation.
- Encourage patient to increase fluid intake to help liquify secretions.
- Tell patient to report the following symptoms to physician: Dizziness, chest pain, palpitations, muscle spasms, headache, difficult urination, dyspnea or nervous tremor.
- Explain that if no relief is obtained from normal daily dose, call physician instead of increasing dose. Also if > 3 aerosol treatments are needed in 24 hours, notify physician.
- Tell patient to wait at least 1 to 2 min before administering second inhalation.
- Instruct patient that regular, consistent use of medication is required for maximum benefits.
- Explain benefits of and demonstrate technique for postural drainage and chest vibration.
- Instruct patient not to take any otc medications without consulting physician.
- Emphasize that it is important to avoid getting aerosol medication in eyes.
- Tell patient to avoid smoking, smoke-filled rooms, and persons with respiratory infections.
- Explain how to use and care for inhalers and any other respiratory equipment.
Contraindication ::
(pihr-BYOO-tuh-role ASS-uh-TATE) |
Maxair Inhaler, Maxair Autohaler |
Class: Bronchodilator/Sympathomimetic |
Action Produces bronchodilation by relaxing bronchial smooth muscle through beta-2 receptor stimulation.
Indications Prevention and treatment of reversible bronchospasm associated with asthma or other obstructive pulmonary diseases.
Contraindications Hypersensitivity to drug components; cardiac arrhythmias associated with tachycardia.
Route/Dosage
ADULTS & CHILDREN ³ 12 YR: Inhalation 1 to 2 inhalations q 4 to 6 hr; not to exceed 12 inhalations/day.
Interactions
MAO inhibitors, tricyclic antidepressants: May increase the effects of pirbuterol.
Lab Test Interferences None well documented.
Adverse Reactions
CV: Palpitations; tachycardia; BP changes; chest tightness/pain/discomfort; angina; arrhythmias/skipped beats. CNS: Tremor; anxiety; confusion; fatigue; dizziness; nervousness; headache; weakness; hyperactivity/hyperkinesia/excitement; insomnia. EENT: Dry nose; throat irritation. GI: GI distress; dry mouth; diarrhea; nausea/vomiting. RESP: Cough; throat irritation. OTHER: Flushing; anorexia/appetite loss; unusual/bad taste; taste/smell change.
Precautions
Pregnancy: Category C. Children: Safety and efficacy in children £ 12 years of age have not been established. Lactation: Undetermined. Elderly: Lower doses may be required. Cardiovascular effects: Toxic symptoms in patients with cardiovascular disorders may occur. CNS effects: CNS stimulation may occur; use cautiously in patients with history of seizure or hyperthyroidism. Diabetes: Dosage adjustment of insulin or oral hypoglycemic agent may be required. Excessive use: Paradoxical bronchospasm and cardiac arrest have been associated with excessive inhalant use. Hypokalemia: Decreases in potassium levels have occurred. Labor and delivery: May inhibit uterine contractions and delay preterm labor. Tolerance: If previously effective dose fails to provide relief therapy may need to be reassessed.
PATIENT CARE CONSIDERATIONS |
|
Administration/Storage
- Give pressurized inhalation during second half of breath intake.
- If > 1 inhalation is needed, wait 1 to 2 minutes before administering second dose.
- Discard any discolored solutions of drug.
- Store at room temperature in light-resistant container.
Assessment/Interventions
- Obtain patient history, including drug history and any known allergies.
- Obtain baseline ABGs prior to initiation of therapy.
- Assess BP and pulse before and after each dose.
- Assess for CNS response, and adjust dose and frequency accordingly.
- To prevent respiratory depression, administer oxygen based on ABGs and symptoms.
- Assess vital capacity and forced expiratory volume.
- If 3 to 5 aerosol treatments have been given within 6 to 12 hours with minimal relief, notify physician and do not give further treatment.
OVERDOSAGE: SIGNS & SYMPTOMS |
|
Tremor, palpitations, tachycardia, elevated blood pressure, anginal pain, hypokalemia, seizures |
|
Patient/Family Education
- Advise patient to take drug early in day to prevent insomnia.
- Explain that implementing therapy in morning and after meals may reduce fatigue and improve lung ventilation.
- Encourage patient to increase fluid intake to help liquify secretions.
- Tell patient to report the following symptoms to physician: Dizziness, chest pain, palpitations, muscle spasms, headache, difficult urination, dyspnea or nervous tremor.
- Explain that if no relief is obtained from normal daily dose, call physician instead of increasing dose. Also if > 3 aerosol treatments are needed in 24 hours, notify physician.
- Tell patient to wait at least 1 to 2 min before administering second inhalation.
- Instruct patient that regular, consistent use of medication is required for maximum benefits.
- Explain benefits of and demonstrate technique for postural drainage and chest vibration.
- Instruct patient not to take any otc medications without consulting physician.
- Emphasize that it is important to avoid getting aerosol medication in eyes.
- Tell patient to avoid smoking, smoke-filled rooms, and persons with respiratory infections.
- Explain how to use and care for inhalers and any other respiratory equipment.
Drug Precautions ::
(pihr-BYOO-tuh-role ASS-uh-TATE) |
Maxair Inhaler, Maxair Autohaler |
Class: Bronchodilator/Sympathomimetic |
Action Produces bronchodilation by relaxing bronchial smooth muscle through beta-2 receptor stimulation.
Indications Prevention and treatment of reversible bronchospasm associated with asthma or other obstructive pulmonary diseases.
Contraindications Hypersensitivity to drug components; cardiac arrhythmias associated with tachycardia.
Route/Dosage
ADULTS & CHILDREN ³ 12 YR: Inhalation 1 to 2 inhalations q 4 to 6 hr; not to exceed 12 inhalations/day.
Interactions
MAO inhibitors, tricyclic antidepressants: May increase the effects of pirbuterol.
Lab Test Interferences None well documented.
Adverse Reactions
CV: Palpitations; tachycardia; BP changes; chest tightness/pain/discomfort; angina; arrhythmias/skipped beats. CNS: Tremor; anxiety; confusion; fatigue; dizziness; nervousness; headache; weakness; hyperactivity/hyperkinesia/excitement; insomnia. EENT: Dry nose; throat irritation. GI: GI distress; dry mouth; diarrhea; nausea/vomiting. RESP: Cough; throat irritation. OTHER: Flushing; anorexia/appetite loss; unusual/bad taste; taste/smell change.
Precautions
Pregnancy: Category C. Children: Safety and efficacy in children £ 12 years of age have not been established. Lactation: Undetermined. Elderly: Lower doses may be required. Cardiovascular effects: Toxic symptoms in patients with cardiovascular disorders may occur. CNS effects: CNS stimulation may occur; use cautiously in patients with history of seizure or hyperthyroidism. Diabetes: Dosage adjustment of insulin or oral hypoglycemic agent may be required. Excessive use: Paradoxical bronchospasm and cardiac arrest have been associated with excessive inhalant use. Hypokalemia: Decreases in potassium levels have occurred. Labor and delivery: May inhibit uterine contractions and delay preterm labor. Tolerance: If previously effective dose fails to provide relief therapy may need to be reassessed.
PATIENT CARE CONSIDERATIONS |
|
Administration/Storage
- Give pressurized inhalation during second half of breath intake.
- If > 1 inhalation is needed, wait 1 to 2 minutes before administering second dose.
- Discard any discolored solutions of drug.
- Store at room temperature in light-resistant container.
Assessment/Interventions
- Obtain patient history, including drug history and any known allergies.
- Obtain baseline ABGs prior to initiation of therapy.
- Assess BP and pulse before and after each dose.
- Assess for CNS response, and adjust dose and frequency accordingly.
- To prevent respiratory depression, administer oxygen based on ABGs and symptoms.
- Assess vital capacity and forced expiratory volume.
- If 3 to 5 aerosol treatments have been given within 6 to 12 hours with minimal relief, notify physician and do not give further treatment.
OVERDOSAGE: SIGNS & SYMPTOMS |
|
Tremor, palpitations, tachycardia, elevated blood pressure, anginal pain, hypokalemia, seizures |
|
Patient/Family Education
- Advise patient to take drug early in day to prevent insomnia.
- Explain that implementing therapy in morning and after meals may reduce fatigue and improve lung ventilation.
- Encourage patient to increase fluid intake to help liquify secretions.
- Tell patient to report the following symptoms to physician: Dizziness, chest pain, palpitations, muscle spasms, headache, difficult urination, dyspnea or nervous tremor.
- Explain that if no relief is obtained from normal daily dose, call physician instead of increasing dose. Also if > 3 aerosol treatments are needed in 24 hours, notify physician.
- Tell patient to wait at least 1 to 2 min before administering second inhalation.
- Instruct patient that regular, consistent use of medication is required for maximum benefits.
- Explain benefits of and demonstrate technique for postural drainage and chest vibration.
- Instruct patient not to take any otc medications without consulting physician.
- Emphasize that it is important to avoid getting aerosol medication in eyes.
- Tell patient to avoid smoking, smoke-filled rooms, and persons with respiratory infections.
- Explain how to use and care for inhalers and any other respiratory equipment.
Drug Side Effects ::
(pihr-BYOO-tuh-role ASS-uh-TATE) |
Maxair Inhaler, Maxair Autohaler |
Class: Bronchodilator/Sympathomimetic |
Action Produces bronchodilation by relaxing bronchial smooth muscle through beta-2 receptor stimulation.
Indications Prevention and treatment of reversible bronchospasm associated with asthma or other obstructive pulmonary diseases.
Contraindications Hypersensitivity to drug components; cardiac arrhythmias associated with tachycardia.
Route/Dosage
ADULTS & CHILDREN ³ 12 YR: Inhalation 1 to 2 inhalations q 4 to 6 hr; not to exceed 12 inhalations/day.
Interactions
MAO inhibitors, tricyclic antidepressants: May increase the effects of pirbuterol.
Lab Test Interferences None well documented.
Adverse Reactions
CV: Palpitations; tachycardia; BP changes; chest tightness/pain/discomfort; angina; arrhythmias/skipped beats. CNS: Tremor; anxiety; confusion; fatigue; dizziness; nervousness; headache; weakness; hyperactivity/hyperkinesia/excitement; insomnia. EENT: Dry nose; throat irritation. GI: GI distress; dry mouth; diarrhea; nausea/vomiting. RESP: Cough; throat irritation. OTHER: Flushing; anorexia/appetite loss; unusual/bad taste; taste/smell change.
Precautions
Pregnancy: Category C. Children: Safety and efficacy in children £ 12 years of age have not been established. Lactation: Undetermined. Elderly: Lower doses may be required. Cardiovascular effects: Toxic symptoms in patients with cardiovascular disorders may occur. CNS effects: CNS stimulation may occur; use cautiously in patients with history of seizure or hyperthyroidism. Diabetes: Dosage adjustment of insulin or oral hypoglycemic agent may be required. Excessive use: Paradoxical bronchospasm and cardiac arrest have been associated with excessive inhalant use. Hypokalemia: Decreases in potassium levels have occurred. Labor and delivery: May inhibit uterine contractions and delay preterm labor. Tolerance: If previously effective dose fails to provide relief therapy may need to be reassessed.
PATIENT CARE CONSIDERATIONS |
|
Administration/Storage
- Give pressurized inhalation during second half of breath intake.
- If > 1 inhalation is needed, wait 1 to 2 minutes before administering second dose.
- Discard any discolored solutions of drug.
- Store at room temperature in light-resistant container.
Assessment/Interventions
- Obtain patient history, including drug history and any known allergies.
- Obtain baseline ABGs prior to initiation of therapy.
- Assess BP and pulse before and after each dose.
- Assess for CNS response, and adjust dose and frequency accordingly.
- To prevent respiratory depression, administer oxygen based on ABGs and symptoms.
- Assess vital capacity and forced expiratory volume.
- If 3 to 5 aerosol treatments have been given within 6 to 12 hours with minimal relief, notify physician and do not give further treatment.
OVERDOSAGE: SIGNS & SYMPTOMS |
|
Tremor, palpitations, tachycardia, elevated blood pressure, anginal pain, hypokalemia, seizures |
|
Patient/Family Education
- Advise patient to take drug early in day to prevent insomnia.
- Explain that implementing therapy in morning and after meals may reduce fatigue and improve lung ventilation.
- Encourage patient to increase fluid intake to help liquify secretions.
- Tell patient to report the following symptoms to physician: Dizziness, chest pain, palpitations, muscle spasms, headache, difficult urination, dyspnea or nervous tremor.
- Explain that if no relief is obtained from normal daily dose, call physician instead of increasing dose. Also if > 3 aerosol treatments are needed in 24 hours, notify physician.
- Tell patient to wait at least 1 to 2 min before administering second inhalation.
- Instruct patient that regular, consistent use of medication is required for maximum benefits.
- Explain benefits of and demonstrate technique for postural drainage and chest vibration.
- Instruct patient not to take any otc medications without consulting physician.
- Emphasize that it is important to avoid getting aerosol medication in eyes.
- Tell patient to avoid smoking, smoke-filled rooms, and persons with respiratory infections.
- Explain how to use and care for inhalers and any other respiratory equipment.
Drug Mode of Action ::
(pihr-BYOO-tuh-role ASS-uh-TATE) |
Maxair Inhaler, Maxair Autohaler |
Class: Bronchodilator/Sympathomimetic |
Action Produces bronchodilation by relaxing bronchial smooth muscle through beta-2 receptor stimulation.
Indications Prevention and treatment of reversible bronchospasm associated with asthma or other obstructive pulmonary diseases.