Details About Generic Salt ::  Budesonide 

Main Medicine Class:: Respiratory System   Sub Medicine Class ::  Drugs For Asthma,COPD,ARDS

6A. DRUGS FOR ASTHMA/COPD/ARDS in 6. RESPIRATORY SYSTEM
BUDESONIDE
CORTICOSTEROID (INHALATION) | ANTI-ASTHMA, ANTI-INFLAMMATORY
also comes under 2B. Corticosteroids in 2. Ear, Nose & Throat (ENT),   7H. Drugs for Inflammatory Bowel Disease in 7. Gastrointestinal System
PK: D: 2.2-3.9 L/kg M: Liver E: Urine

Indications & Dose: ASTHMA Inh Adult MDI: 400µg/day in 2 divided doses may increase dose in severe asthma (upto 1.6mg or 2mg/day), MD: 200-400µg/day, Dry powder inhaler: 200-800µg/day as 2 divided doses/single daily dose max 800µg BID, Nebulizer: 1-2mg BID, MD 0.5-1mg BID Child MDI: 50-400µg BID, Nebulizer: 3 months-12yr: Initially 0.5-1mg BID, MD 0.25-0.5mg BID | CROHN’S DISEASE Mild-to-moderate PO Adult Delayed release capsules: 9mg/day (in morning) 8 wks. For clinical remission MD 6mg/day 3 months. If symptoms are controlled, then discontinue by gradually tapering the doseinvolving ileum and/or ascending colon | CROUP Inh Child Nebuliser suspension: >1 month: 2mg in 1 or 2 divided doses separated by 30min, may repeat after 12h if required | NASAL POLYPS NSL Adult 1 spray (containing 64/100µg) into each nostril BID 3months Child >12yr: Same as adult dose | RHINITIS NSL Adult Initially 2 sprays into each nostril OD in the morning or 1 spray into each nostril BID, may reduce to dose (1 spray into each nostril OD) & continued for 3 month Child >12yr: Same as adult dose

Contra: Hypersensitivity

Precautions: HF, recent MI, HTN, DM, epilepsy, glaucoma, hypothyroidism, hepatic failure, osteoporosis, PUD, psychoses/severe affective disorders, renal impairment, children, elderly, quiescent TB

ADR: Serious: Increased susceptibility to infect, increased severity of varicella & measles, ocular changes, mental & neurological disturbances, benign intracranial HTN, acute pancreatitis, avascular necrosis of bone, adrenal atrophy, cushingoid symptoms, flushing, hypersensitivity reactions, corneal ulcers, raised IOP, reduced visual function, Others: Menstrual irregularities, hyperhidrosis, skin thinning, increased bruising, ecchymoses, dryness, hoarseness & candidiasis of the mouth/throat, irritation, urticaria, weight gain or loss, hyperglycemia

DDI: Serious Metformin/Glibenclamide deterioration in diabetic control, Itraconazole increases drug levels, Ritonavir increases the drug levels, Clarithromycin leads to cushing’s syndrome, Colestyramine reduces the absorption of drug

We would like to keep you updated with special notifications.