The Brand Name NACXIME Has Generic Salt :: Cefotaxime 

NACXIME  Is From Company Nac Int. Priced :: Rs. 23.5

NACXIME have Cefotaxime is comes under Sub class Cephalosporins of  Main Class Anti Infectives

Main Medicine Class:: Anti Infectives  Sub Medicine Class :: Cephalosporins 

 Salt Name :  OR Generic Name Form Price : MRP /Probable Packing
Cefotaxime  INJ  Rs. 23.5  V.
Brand Name Company / Manufacturers Strength Unit Price / V.
 NACXIME  Nac Int.  500MG  V. Rs. 23.5

Company  Brand Name  Salt Combination Main Medical Class Sub Medical Class
 From Nac Int. :: NACXIME  Cefotaxime  Anti Infectives Cephalosporins

Indications for Drugs ::

Pneumonia, Meningitis, Peritonitis, Pelvic inflammatory disease, Endometritis, Pelvic cellulitis, Gonorrhea, Skin and skin structure infections, Respiratory tract infections, Urinary tract infections, Bacteremia/Septicemia, Bone and/or joint infections

Drug Dose ::

Adult: IV/IM Susceptible infections 1-2 g 4-12 hrly. Max: 12 g/day. Surgical prophylaxis 1 g 30-90 mins before procedure. Gonorrhoea 0.5-1 g as a single dose. Children: The usual dosage range is 100-150 mg/kg/day in 2 to 4 divided doses. However, in very severe infections doses of up to 200 mg/kg/day may be required. Neonates: The recommended dosage is 50 mg/kg/day in 2 to 4 divided doses. In severe infections 150-200 mg/kg/day in divided doses have been given.

Contraindication ::

Hypersensitivity to cephalosporins.

Drug Precautions ::

History of penicillin allergy; colitis; impaired renal function; pregnancy, lactation.

Drug Side Effects ::

Pain at inj site; hypersensitivity reactions, rash, pruritus; diarrhoea, nausea, vomiting; candidiasis; eosinophilia, neutropenia, leucopenia, thrombocytopenia. Potentially Fatal: Anaphylactic reaction; nephrotoxicity.

Pregnancy category ::
Pregnancy category


Drug Mode of Action ::  

Cefotaxime binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.

Drug Interactions ::

Probenecid decreases cefotaxime elimination. Potentially Fatal: Nephrotoxicity with furosemide and aminoglycosides.


Disclaimer ::

The Information available on this site is for only Informational Purpose , before any use of this information please consult your Doctor .Price of the drugs indicated above may not match to real price due to many possible reasons may , including local taxes etc.. These are only approximate indicative prices of the drug.


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